Associate Materials Scientist
About The Position
The Associate Scientist provides laboratory support in synthesizing salt forms and polymorphs of drug candidates and evaluating their suitability as drug substances for chemical manufacturing and pharmaceutical formulation. The role conducts solid-form and particle characterization of materials relevant to pharmaceutical products and uses contemporary Materials Science techniques to address scientific problems. Based in Groton, Connecticut, the position supports multidisciplinary teams in planning and carrying out crystallization, polymorph, salt, co-crystal, and active pharmaceutical ingredient (API) particle screening and characterization activities. The scientist collaborates with colleagues in Medicinal Chemistry, Formulation, and Biopharmaceutics on strategies for solid-form selection for clinical studies, contributes to new scientific approaches and organizational knowledge, and maintains accurate, contemporaneous records in the electronic laboratory notebook system.
Requirements
- Bachelor’s degree (BS) with at least 2 years of experience, or a Master’s degree (MS), in pharmaceutical science, chemistry, chemical engineering, or a related field.
- Experience with solid-state characterization techniques, such as X-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, or spectroscopy.
- Strong data analysis and interpretation skills.
- Experience solving Materials Science problems, such as solid-state chemistry and particle characterization, using experimental approaches and team collaboration.
- Understanding of physical, analytical, and organic chemistry.
- Good organizational skills, ability to work independently, and excellent oral and written communication skills.
- Strong interest and motivation to learn new technologies and concepts.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Nice To Haves
- Strong pharmaceutical, API, or small-molecule testing experience for drug production.
- Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR.
- Some programming experience.
Responsibilities
- Conduct solid-state characterization of small molecules of pharmaceutical relevance, including techniques such as X-ray powder diffraction, thermal analysis, moisture sorption, microscopy, and spectroscopy.
- Support multidisciplinary teams in defining and implementing crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
- Support multidisciplinary teams in defining and implementing API particle characterization activities according to project timelines.
- Conduct physical and surface characterization of pharmaceutical powders, including particle size and shape, surface energy, and surface roughness.
- Collaborate with colleagues in Medicinal Chemistry, Formulation, and Biopharmaceutics to define and implement screening and characterization strategies for solid-form selection for clinical studies.
- Solve scientific problems using contemporary Materials Science experimental techniques.
- Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
- Make contemporaneous and accurate entries in the electronic laboratory notebook system according to accepted good practice.
Benefits
- Comprehensive medical coverage
- Dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
