Associate Director, Operations Network and Strategy

Arrowhead Pharmaceuticals•San Diego, CA

9d•$150,000 - $180,000•Onsite

About The Position

Arrowhead Pharmaceuticals, Inc. is a commercial stage biopharmaceutical company focused on developing medicines for intractable diseases by silencing the genes that cause them. The company utilizes a broad portfolio of RNA chemistries and efficient delivery methods to trigger RNA interference, leading to rapid, deep, and durable gene knockdown. Arrowhead's RNAi-based therapeutics leverage this natural gene silencing pathway. The company is dedicated to developing innovative drugs for genetic diseases, often characterized by the overproduction of disease-involved proteins. Their versatile RNAi technologies have the potential to address conditions across virtually any therapeutic area and target diseases not addressable by small molecules and biologics. Arrowhead is a leader in applying RNAi to diseases beyond the liver, with a clinical pipeline targeting liver and lung diseases and a promising preclinical pipeline. The company's headquarters are in Pasadena, CA, with R&D teams in Madison, WI & San Diego, CA, and a manufacturing facility in Verona, WI. Arrowhead employees are described as nimble, science-driven innovators collaborating to bring new therapies to patients.

Requirements

BS in Business Administration, Supply Chain/Logistics, Engineering, or other field related to the essential duties of this role.
8+ years of relevant industry experience (7+ years in fast paced cGMP environments; 5+ years in a supply chain leadership role within the pharmaceutical industry.)
Exhibits excellent interpersonal communication, project management, collaboration, and analytical skills.
Strong MS Excel, PowerPoint, and Word skills.
Experience using Smartsheet or other work management software.
Proficient generating and presenting operational and financial metrics/KPI’s.
Thorough understanding of and experience with some aspect of technical operations or CMC.
Demonstrated ability to effectively lead and influence cross-functional teams not under direct organizational reporting lines to communicate challenging goals and achieve objectives.
Quick learner with the ability to handle multiple tasks simultaneously, maintain focus, and adapt to a variety of challenges.
Exhibits creativity in adapting to changing situations, development of contingency plans and comfortable with making decisions.

Nice To Haves

Able to lead and coordinate large, complex strategy projects, with minimal direction
Experience developing operations network strategies for a growing global market

Responsibilities

Lead development of end-to-end operations network strategy aligned with enterprise growth objectives.
Design and optimize manufacturing, distribution, and supply network footprint (internal and external).
Conduct scenario modeling to evaluate capacity expansion, site selection, outsourcing, nearshoring, and risk mitigation strategies.
Develop long-term capacity and capital investment roadmaps.
Build and maintain advanced network models to support demand growth, product lifecycle changes, and geographic expansion.
Evaluate trade-offs across cost, service, resilience, sustainability, and risk.
Lead cross-functional S&OP/S&OE inputs related to network capacity and constraints.
Establish KPIs and dashboards to monitor network performance.
Identify and lead high-impact cost, productivity, and service improvement initiatives.
Support make-vs-buy decisions and strategic supplier partnerships.
Drive network resilience planning, including dual sourcing, inventory strategy, and contingency planning.
Partner with Digital/IT teams to enhance data, modeling tools, and planning systems.
Develop business cases for capital investments, site expansions, and strategic initiatives.
Quantify financial impact of network decisions (NPV, IRR, cost-to-serve analysis).
Partner with Finance to align operational strategy with financial targets.
Serve as a trusted advisor to senior leadership on operations strategy.
Present recommendations to executive leadership and Board-level stakeholders (as applicable).
Lead and develop a team (Director level may include people leadership; Associate Director may lead through influence).