Associate Director, Development Project Management

Definium Therapeutics

6d • $150,000 - $195,000

About The Position

Definium Therapeutics is a late-stage clinical biopharmaceutical company focused on developing accessible treatments for psychiatric disorders using psychedelics. Our lead product candidate targets generalized anxiety, major depressive disorder, and posttraumatic stress disorder, with a pipeline including a compound for autism spectrum disorder. We aim to address the underlying causes of psychiatric and neurological disorders and transform mental health care. We are seeking an Associate Director, Development Project Management to serve as a strategic execution partner, leading integrated planning, milestone tracking, risk and issue management, and cross-functional execution for assigned programs. The ideal candidate will have strong drug development experience, excellent stakeholder management skills, and the ability to create structure and drive accountability in a fast-paced, lean organization. Experience with late-stage development, regulatory submission planning, and tools like Planisware Enterprise is preferred. The role requires comfort operating in an evolving organization, creating clarity and structure while remaining flexible and pragmatic.

Requirements

• Bachelor’s degree in a scientific, business, operations, or related discipline required.
• Minimum 10 years of overall experience in the pharmaceutical or biotech industry preferred.
• Minimum of 8 years of project/program management experience in the pharmaceutical, biotech, or life sciences industry.
• Strong understanding of end-to-end drug development business processes.
• Experience supporting cross-functional development teams, functional workstreams, or program-level initiatives in a matrixed environment.
• Demonstrated ability to develop and manage integrated project plans, milestones, critical paths, dependencies, risks, issues, assumptions, and decision points.
• Experience working across one or more development functions, such as clinical development, clinical operations, CMC, regulatory affairs, preclinical, translational, commercial, or medical affairs.
• Strong proficiency with Microsoft Office and project management tools, such as Microsoft Project, Planisware Enterprise, Smartsheet, or equivalent systems.

Nice To Haves

• Advanced degree in science, business, operations, or related discipline preferred.
• Experience with late-stage development, regulatory submission planning, and tools such as Planisware Enterprise is preferred.
• Experience in late-phase development organizations or late-stage asset planning preferred.
• Experience supporting NDA, BLA, MAA, major regulatory submissions, or submission-readiness planning preferred.
• Experience using Planisware Enterprise or other portfolio/project management systems in a development environment preferred.
• PMP, Agile, Lean Six Sigma, or other relevant project management certification preferred.

Responsibilities

• Lead development and maintenance of integrated project plans that align program strategy, milestones, deliverables, dependencies, and decision points across key functions, ensuring alignment with sub-team plans.
• Partner with sub-team functional leads to ensure plans are realistic, aligned, and positioned to support successful program execution.
• Drive cross-functional execution by monitoring progress against milestones, deliverables, timelines, resources, and critical path activities.
• Facilitate productive team meetings and ensure clear accountability for decisions, actions, and follow-up activities.
• Proactively identify, assess, and manage risks, issues, assumptions, dependencies, and opportunities that may impact program objectives.
• Partner with teams to develop mitigation strategies, contingency plans, and escalation recommendations to enable informed decision-making.
• Support governance and leadership forums by preparing decision-focused materials, status updates, risk summaries, and recommendations.
• Ensure timely communication and alignment of key program priorities, decisions, milestones, and risks across stakeholders.
• Identify opportunities to improve planning, execution, team effectiveness, and operational processes to enhance organizational performance.

Benefits

• 100% paid health benefits including Medical, Dental and Vision for you and your dependents
• 401(k) program with company match and vesting after the turn of the first month after your start date
• Flexible time off
• Generous parental leave
• Some fun fringe perks!

What This Job Offers

• Job Type: Full-time
• Career Level: Senior