About The Position

This role within Technical Operations’ Commercialization Capabilities and Strategic Projects function builds and strengthens business operations, data, digital tools, and performance insights to support better decisions, effective resource allocation, risk anticipation, and execution as the organization advances toward commercialization and future growth. The role creates an integrated view of Technical Operations priorities, capacity, risks, dependencies, progress, and performance while identifying opportunities to simplify and automate work. Working across Technical Operations and with teams across Vaxcyte, the role translates business needs into practical, scalable solutions that improve visibility, decision-making, and organizational performance. The successful candidate combines business judgment with analytical, systems, and digital fluency, applying data, automation, analytics, and AI to strengthen the organization’s ability to scale. The position is hybrid in San Carlos, California, with a minimum of three days per week onsite. It reports to the Executive Director, Commercialization Capabilities & Strategic Projects. The compensation package includes comprehensive benefits and an equity component; the salary range is $176,000–$206,000 for the San Francisco Bay Area. The role is not eligible for relocation assistance.

Requirements

  • Bachelor’s degree in Business, Operations, Engineering, Data/Analytics, Information Systems, Life Sciences, or a related discipline; other combinations of education and/or experience may be considered.
  • 10+ years of progressive experience in business operations, strategy and operations, portfolio management, analytics, digital transformation, operational excellence, or related disciplines.
  • Demonstrated experience building executive dashboards, KPIs, portfolio views, performance-management systems, and decision-support mechanisms.
  • Strong business and analytical acumen, including the ability to translate complex data into actionable insights and recommendations.
  • Strong understanding of business processes, systems, workflow optimization, data governance, and digital enablement.
  • Demonstrated experience applying automation, analytics, AI, or emerging technologies to practical business problems.
  • Strong cross-functional leadership, facilitation, and executive communication skills, with the ability to influence without direct authority.
  • Ability to operate effectively in a fast-paced, evolving environment and balance near-term business needs with scalable long-term solutions.

Nice To Haves

  • Advanced degree preferred.
  • Experience in biotechnology, pharmaceutical, biopharmaceutical manufacturing, Technical Operations, or another complex regulated environment is strongly preferred.

Responsibilities

  • Build and continuously improve business operating practices that give leaders an integrated view of Technical Operations priorities, initiatives, capacity, risks, dependencies, milestones, and performance.
  • Establish and support portfolio and capacity-management processes for proactive prioritization, resource tradeoffs, and leadership decisions.
  • Support demand intake, strategy realization, and execution-readiness processes with business analysis, data, and decision support.
  • Partner with leaders to identify resource constraints, emerging risks, cross-functional dependencies, and opportunities requiring leadership attention.
  • Develop scalable operating rhythms and business review mechanisms linking strategy, portfolio performance, and organizational decision-making.
  • Develop executive dashboards, KPIs, reporting, and operational insights to improve visibility and enable timely, data-informed decisions.
  • Create shared visibility into priorities, risks, progress, improvement efforts, and performance where transparency improves execution.
  • Translate complex operational data into clear insights, scenarios, tradeoffs, and recommendations for leadership.
  • Establish sustainable performance-management practices connecting strategic priorities to measurable execution and business outcomes.
  • Improve the consistency, accessibility, usability, and governance of data used for Technical Operations decision-making.
  • Identify and implement opportunities to simplify work and improve productivity through digital tools, automation, analytics, and AI-enabled solutions.
  • Translate business needs and process requirements into scalable digital solutions in partnership with IT, data, and functional teams.
  • Lead or coordinate business-side requirements gathering, process design, adoption, and value realization for relevant digital initiatives.
  • Promote thoughtful adoption of new tools and technologies by ensuring solutions address real business needs and integrate into existing ways of working.
  • Evaluate emerging technologies and recommend practical applications that improve operational performance, visibility, or decision quality.
  • Integrate information and workflows across functional boundaries where execution depends on shared visibility and coordinated decision-making.
  • Build repeatable business operations, analytics, and digital capabilities that remain sustainable as Technical Operations grows.
  • Partner closely with the Principal, Business Process Management & Operational Excellence so process design, portfolio management, data, systems, and digital solutions reinforce one another.
  • Build trusted relationships with leaders across Technical Operations and the business, balancing functional needs with broader organizational priorities.

Benefits

  • Comprehensive benefits
  • Equity component
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