Assistant Research Professor in Cryo-EM Studies of Amyloids, Virus/Host Interactions, and Protein Complexes

The Pennsylvania State University•University Park, FL

38d•Onsite

About The Position

This is a term position in the Jiang lab at The Pennsylvania State University, within the Department of Biochemistry and Molecular Biology and the Huck Institutes of the Life Sciences. The lab is equipped with state-of-the-art cryo-EM instruments, including Titan Krios and Talos Arctica TEMs with energy filters and direct electron detectors for single-particle cryoEM and cryo-ET, and a Hydra FIB-SEM for in situ structural studies. The position involves working on cryo-EM structural studies of amyloids in neurodegenerative diseases, virus/host interactions, and protein complexes relevant to cancers using single-particle cryoEM and cryo-ET. Daily tasks include cryo-EM sample preparation/screening, data collection, image processing, 3D reconstruction, and structural modeling/analyses.

Requirements

A Ph.D. degree or its equivalent
Highly self-motivated and passionate for cryo-EM structural studies
Prior experience in cryo-EM sample preparation/screening, data collection, and image processing/3D reconstruction
Prior experiences in protein biochemistry and molecular biology
Ability to work independently and as part of a team
Excellent communication and writing skills

Responsibilities

Work on cryo-EM structural studies of amyloids in neurodegenerative diseases, virus/host interactions, and protein complexes relevant to cancers using single-particle cryoEM and cryo-ET.
Perform cryo-EM sample preparation/screening.
Conduct data collection.
Perform image processing.
Conduct 3D reconstruction.
Perform structural modeling/analyses.
Assist the PI in mentoring junior members in the lab.