Assay Development Scientist, Molecular

NeoGenomics Laboratories•Aliso Viejo, CA
•Onsite

About The Position

NeoGenomics is seeking an Assay Development Scientist to support the company’s cancer reference laboratory mission and contribute to improving patient care. This onsite position is based at the Aliso Viejo, California laboratory and follows a Monday–Friday day shift. The Scientist applies expertise in assay design and validation, including Sanger sequencing, PCR-based testing, and next-generation sequencing (NGS), as well as hands-on sequencing data analysis and interpretation. The role spans wet-lab and data-analysis workflows and contributes to assay development, validation, troubleshooting, and delivery of high-quality data in a regulated laboratory environment.

Requirements

  • At least 8 years of experience with a B.S. or M.S./M.A.; at least 4 years of industry experience with an M.S./M.A.; or at least 2 years of industry experience with a Ph.D.
  • Solid understanding of laboratory and/or analytical techniques.
  • Ability to develop and deliver complex directions and scientific project plans.
  • Ability to accurately and reliably capture and record complex scientific data, with attention to detail.
  • Effective written and verbal communication and ability to use software tools to produce high-impact data presentations.
  • Ability to problem solve independently and escalate issues appropriately and in a timely manner.
  • Ability to work independently and collaboratively within a team environment.
  • Ability to work effectively in a fast-paced, multitasking environment while maintaining production and quality standards.

Nice To Haves

  • Ph.D. in cancer genomics or a related field.

Responsibilities

  • Design, optimize, and validate primers and probes for Sanger sequencing, PCR, and NGS applications.
  • Perform hands-on wet-lab testing for Sanger, PCR, and NGS workflows.
  • Analyze and interpret sequencing data using platforms such as Sequencher, SeqScape, Gene Mapper, Innovigene data analysis suites, and others.
  • Perform variant calling, alignment review, and quality assessment for Sanger and NGS datasets.
  • Identify and troubleshoot data quality issues and recommend corrective actions.
  • Support assay development, RUO/LDT validations, troubleshooting, and performance optimization.
  • Evaluate assay quality metrics and implement improvements as needed.
  • Prepare clear, accurate reports or summaries of sequencing results for internal teams and/or external stakeholders.

Benefits

  • Career coaches
  • Training opportunities
  • HMO and PPO health plan options
  • Company 401(k) match
  • Employee Stock Purchase Program
  • Tuition reimbursement
  • Leadership development
  • 16 days of paid time off plus holidays
  • Wellness courses
  • Employee resource groups
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