Analytical Scientist I

Phosphorex LLC•Hopkinton, MA

About The Position

The Analytical Scientist I works on the Analytical Team, independently performing routine and advanced analytical testing to support development of particulate-based drug delivery systems. The role requires strong liquid chromatography (LC) expertise and involves advanced LC analyses (such as HPLC/UPLC), capillary electrophoresis (CE), and dissolution/in vitro release testing for nucleic acids, APIs, and lipids. The scientist serves as an LC resource for the team and assists with method development and qualification, instrument training for junior staff, and analytical problem-solving and troubleshooting. The role requires working independently and collaboratively across departments and supporting multiple projects in parallel. The position also includes data analysis and reporting, internal presentation of results, maintaining detailed laboratory records, reviewing technical documents such as SOPs, methods, and reports, and assisting with the design of in vitro release and stability studies. The scientist must follow Environmental Health & Safety practices. Work takes place in a laboratory with potential exposure to chemicals; it may involve extended standing and repetitive tasks. Occasional work outside standard office hours (9:00 a.m.–5:30 p.m.) may be needed to meet project requirements.

Requirements

  • Bachelor’s degree in chemistry, pharmacy, or pharmaceutical sciences with 2–5 years of experience, or a master’s degree with 0–1 years of experience.
  • Demonstrated hands-on expertise in liquid chromatography, such as HPLC/UPLC, including method execution, data interpretation, and troubleshooting.
  • Proficiency in Microsoft Office, including Word, Excel, and PowerPoint.
  • Strong analytical and problem-solving skills.
  • Excellent attention to detail and organizational skills.
  • Ability to work independently and as part of a team.
  • Excellent verbal and written communication skills and ability to collaborate cross-functionally.

Nice To Haves

  • Advanced LC expertise, including method development and qualification for particulate drug delivery formulations.
  • Experience with complex analytical testing and data analysis.
  • Familiarity with laboratory safety protocols and EH&S practices.

Responsibilities

  • Independently perform routine analytical testing and advanced analyses with minimal direction.
  • Conduct LC analyses, including HPLC/UPLC, and CE testing for nucleic acids, APIs, and lipids, as well as dissolution and in vitro release testing.
  • Run, troubleshoot, and interpret LC analyses, and serve as an LC resource for the team.
  • Assist in training junior staff on instrument operation and analytical techniques, including LC.
  • Operate and maintain laboratory instruments, including LC systems.
  • Assist in developing and qualifying analytical methods, particularly LC methods.
  • Participate in analytical problem-solving and troubleshooting, including LC method and instrument troubleshooting.
  • Analyze and report data from routine assays and development activities, and present data internally to team members and stakeholders.
  • Maintain detailed and accurate laboratory notebooks.
  • Review SOPs, methods, reports, and other technical documents for accuracy and compliance.
  • Assist in designing in vitro release and stability studies to support product development.
  • Follow EH&S practices and protocols to maintain a safe working environment.
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