Administrative Director, Clinical Trial Center for Neurotherapeutics

Mass General Brigham•Somerville, MA

1d•Hybrid

About The Position

The Mass General Brigham Neuroscience Institute (NSI) seeks an accomplished Administrative Director to lead the operational and administrative infrastructure of the NSI Clinical Trial Center for Neurotherapeutics (CTC). This full-time leadership role is responsible for overseeing all aspects of clinical trial operations across a diverse and rapidly expanding portfolio, including regulatory operations, site management, multi-site coordination, compliance frameworks, industry partnerships, and performance oversight. This role requires a highly experienced leader with deep expertise in multisite clinical trial project management and regulatory science, and a comprehensive understanding of the full clinical trial lifecycle from protocol design and startup through conduct, monitoring, and closeout. The administrative director will play a critical role in building and implementing the vision, structure, and infrastructure of the CTC, ensuring effective and streamlined coordination between the central coordinating center and all participating sites. The Administrative Director will partner closely with the Director of the Clinical Trial Center and will report to the Senior Research Administrator for the NSI. This is a strategic, hands-on leadership role that calls for strong management skills, collaboration across teams, and the ability to work effectively with MGB Clinical Trial office leadership, investigators, industry sponsors, regulatory partners, and internal groups such as biostatistics, finance, and clinical operations teams. The CTC portfolio includes coordination of adult and pediatric studies, inpatient and outpatient trials, innovative gene and cell-based therapeutics and biorepositories. The Administrative Director will ensure operational excellence, regulatory rigor, and high quality execution across all program areas.

Requirements

Bachelor’s degree in related field required; advanced scientific degree (MS, PhD) preferred
10+ years leadership experience in clinical trial coordination and research administration
Extensive regulatory and compliance experience
Demonstrated leadership of multi-site clinical trials and site management programs
Experience supervising teams and managing complex operational programs
Exceptional organizational skills and ability to organize time and priorities effectively, asking for direction when appropriate.
Flexibility to work independently and to handle multiple tasks and deadline pressures.
Skills to work efficiently and effectively and strive to do so in all aspects of position.
Ability to effectively manage day-to-day operations, establish and maintain policies and procedures, monitor service statistics, and coordinate space and infrastructure issues.
Ability to engender these skills among staff.
Ability to skillfully handle issues of sensitive nature with respect to confidentiality, abiding by institutional guidelines.
Ability to recruit, train and supervise staff and to ensure that performance evaluations, payroll, employee changes and other HR transactions are completed in an accurate and timely manner.
Ability to provide support, direction and development to staff.
Extensive knowledge regarding financial, operational, personnel and research management, business planning, project management etc.
Sufficient knowledge to improve, enhance, or upgrade complex financial, operational and technical systems.
Ability to identify issues/projects and initiates plans to address; Demonstrates forthrightness and integrity.
Ability to develop a common vision for diverse constituents, engender teamwork, communicate effectively, sell ideas, and take ownership and responsibility for activities.
Ability to appropriately evaluate all aspects of a situation and to independently make appropriate and timely decisions.
Effective financial and analytical skills, including ability to develop and monitor budgets and review and address statistics and issues to ensure revenue maximization.
Ability to ensure timely submission and review of budgets and performance evaluations.
Ability to handle sensitive and confidential matters discreetly and to ensure confidentiality guidelines (including HIPAA) are maintained by staff.
Ability to conceptualize and conduct complex analysis (financial and operational).
Excellent interpersonal/communications skills and a good command of English language, including medical and scientific terminology.
Exceptional computer skills, including operating systems, word processing, database, electronic mail, Internet, spreadsheets, and other office management systems.
Knowledge in all aspects of safety and ability to ensure a safe environment for patients, staff and laboratory subjects, including specific regulatory requirements (e.g. TJC, CMS, HIPAA), MGH, NIH, federal and private sponsor guidelines, etc.

Nice To Haves

advanced scientific degree (MS, PhD) preferred

Responsibilities

Provide strategic and operational leadership for the day-to-day management of the Clinical Trial Center.
Oversee regulatory and compliance operations, ensuring adherence to federal, state, institutional, and sponsor requirements.
Direct staffing strategy including workforce planning, recruitment, onboarding, training, performance management and retention of a high-performing, multidisciplinary team.
Provide direct supervision to multiple direct reports and foster a culture of accountability, collaboration, and continuous improvement.
Lead quality oversight initiatives and implement process improvements to enhance efficiency, accuracy, and audit/regulatory readiness across all trials.
Drive business development efforts and serve as a key liaison for pharmaceutical, biotechnology, and device company partnerships
Provide support for teams conducting clinical research and resources to track performance and ensure efficiency.
Partner with the Center Director and the NSI Director of Finance on financial planning, budgeting, forecasting, and allocation of operational resources to support sustainable growth.
Partner with the NSI Executive Director, Clinical Trial Center Director and MGB development team on philanthropy proposals and reporting.
Promote a high-performing culture grounded in collaboration, innovation, regulatory excellence, and patient-centered research excellence.
Provides strategic financial leadership for clinical trial programs, including budgeting, financial planning, and oversight of sponsor-funded and grant-supported activities.
Oversees direct program resources, including staffing, overtime, and operational expenses.
Maintains sensitive fiscal information and ensures appropriate internal controls are in place.
Direct reports are anticipated as the function grows, this role will play a key part in building and leading the team.
Provides broad oversight of site clinical research administrative operations, serving as a leader, subject matter expert, and resource to staff across clinical trials units.