2027 Summer Co-op Process Chemistry, Cambridge, MA

Sanofi•Cambridge, MA

6d•Onsite

About The Position

Sanofi is seeking a highly motivated Summer Co-op to join its Process Chemistry team within the CMC Synthetics organization. The team develops synthetic routes, optimizes chemistry, and designs commercial manufacturing processes for drug substances undergoing clinical development. Its work emphasizes innovative routes, concepts, and technologies that make manufacturing more efficient, affordable, environmentally benign, and intrinsically safe. The co-op will contribute to the development and optimization of synthetic pathways and manufacturing processes, using a range of chemistry methods and technologies. The role includes planning and conducting experiments, applying green chemistry principles, characterizing compounds, analyzing results, maintaining electronic laboratory notebooks, and working safely in accordance with company requirements. The position is based in Cambridge, Massachusetts, lasts six months, and requires 40 hours per week, Monday through Friday.

Requirements

Currently enrolled in a doctoral degree program in Chemistry or a related field.
Permanently authorized to work in the United States without requiring employment visa sponsorship at the time of application or in the future.
Enrolled in an accredited college or university throughout the co-op/internship.
Able to relocate to the office location and work 40 hours per week, Monday through Friday, for the full duration of the co-op/internship.

Nice To Haves

Completed chemistry coursework and laboratory coursework.
Experience using analytical instruments such as NMR and LCMS to interpret analytical data and fully characterize novel organic compounds.

Responsibilities

Contribute to the design and optimization of novel, efficient synthetic pathways for drug substances in clinical development to demonstrate synthetic viability.
Use chemistry tools and methods to develop and optimize commercial processes for selected drug substance routes, potentially including photochemistry, biocatalysis, flow chemistry, electrochemistry, online analysis/PAT, high-throughput experimentation, structural analysis, computational chemistry, and AI/ML and predictive tools.
Design, plan, and execute experiments to optimize reaction, purification, and isolation unit operations, guided by technical risk assessments, to deliver safe, efficient, robust, and scalable manufacturing processes for batch or continuous formats.
Learn to apply green chemistry principles to R&D programs and develop sustainable manufacturing routes.
Develop or apply analytical techniques for structural characterization and interpretation, including NMR and LCMS.
Analyze data, interpret experimental results, and design next steps in collaboration with multiple mentors.
Maintain electronic laboratory notebooks according to SOP and provide detailed experimental procedures.
Communicate and interact professionally and courteously with staff and team members.
Work safely and efficiently in the laboratory according to HSE guidelines and comply with mandatory company requirements.