2027 Summer Co-op Process Chemistry, Cambridge, MA

Sanofi•Cambridge, MA

5d•Onsite

About The Position

Sanofi is seeking a motivated Summer Co-op to join its Process Chemistry team, part of the CMC Synthetics organization, in Cambridge, Massachusetts. The team develops and optimizes synthetic routes and designs commercial manufacturing processes for drug substances in clinical development. Its work focuses on innovative routes, concepts, and technologies that improve efficiency, affordability, environmental impact, and process safety. The co-op will contribute to developing and optimizing synthetic pathways and manufacturing processes, planning and conducting experiments, applying green chemistry principles, and using analytical and other chemistry tools. The role includes interpreting data in collaboration with mentors, maintaining electronic laboratory notebooks, and working safely and compliantly in the laboratory. The position lasts six months and requires working 40 hours per week, Monday through Friday, and relocating to the office location.

Requirements

Currently enrolled in a doctoral degree program in Chemistry or a related field.
Must be permanently authorized to work in the United States without requiring employment visa sponsorship at application or in the future.
Must remain enrolled in an accredited college or university throughout the co-op/internship.
Must be able to relocate to the office location and work 40 hours per week, Monday through Friday, for the full duration of the co-op/internship.

Nice To Haves

Completed chemistry coursework and laboratory coursework.
Experience using analytical instruments such as NMR and LCMS to interpret analytical data and fully characterize novel organic compounds.

Responsibilities

Contribute to the design and optimization of novel, efficient synthetic pathways for drug substances undergoing clinical development.
Use chemistry tools and methods to develop and optimize commercial processes, including photochemistry, biocatalysis, flow chemistry, electrochemistry, online analysis/PAT, high-throughput experimentation, structural analysis, computational chemistry, and AI/ML and predictive tools.
Design, plan, and execute experiments to optimize reaction, purification, and isolation unit operations, guided by technical risk assessments.
Help deliver safe, efficient, robust, and scalable drug-substance manufacturing processes for batch or continuous formats.
Learn to apply green chemistry principles to R&D programs and develop sustainable manufacturing routes.
Develop or apply analytical techniques for structural characterization and interpretation, including NMR and LCMS.
Analyze data, interpret experimental results, and design next steps in collaboration with multiple mentors.
Maintain electronic laboratory notebooks according to SOPs and provide detailed experimental procedures.
Communicate and interact professionally and courteously with staff and team members.
Operate safely and efficiently in the laboratory according to HSE guidelines and comply with mandatory company requirements.