Visiting Scientist – Murphy Lab

The Wistar Institute•Philadelphia, PA

13d•Onsite

About The Position

The Wistar Institute is a world leader in early-stage discovery science in the areas of cancer, immunology, and infectious disease. Wistar is committed to accelerating research advances from bench to bedside through brilliant science and distinctive approaches to collaboration among scientific investigators and academic and industry partners. Wistar’s dynamic environment supports the advancement of discoveries that will change the future of human health. The Wistar Institute has an opening for a Visiting Scientist to join the laboratory of Dr. Maureen Murphy to study the p53 tumor suppressor protein using chromatin biology techniques and mouse models. The lab studies the genetics of the p53 tumor suppressor protein. The laboratory work focuses on genetic variants of p53 that exist in populations of African-descent (P47S and Y107H) and Ashkenazi Jewish descent (G334R). This work seeks to understand the impact of these genetic variants of p53 on cancer risk and the efficacy of cancer therapy. The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Wistar provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities.

Requirements

PhD (or equivalent) degree or close to obtaining their doctoral degree.
Expertise in genomics and pre-clinical models is strongly desired.

Responsibilities

Study the p53 tumor suppressor protein using chromatin biology techniques and mouse models.
Focus on genetic variants of p53 that exist in populations of African-descent (P47S and Y107H) and Ashkenazi Jewish descent (G334R).
Understand the impact of these genetic variants of p53 on cancer risk and the efficacy of cancer therapy.