Vice President, Process Development

Vir Biotechnology•San Francisco, CA

8h•$300,000 - $350,000•Hybrid

About The Position

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies. Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company. We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best. Vir Biotechnology is seeking a Vice President, Process Development to lead our global Drug Substance Process Development and Manufacturing Sciences & Technology (MSAT) organization. Reporting to the Chief Technology Officer, this leader will oversee process development, technology transfer, manufacturing support, and lifecycle management across Vi Bio’s portfolio. You will lead a high-performing team and define and execute drug substance strategies for monoclonal antibodies, T-cell engagers, and other large molecule biologics within a highly outsourced manufacturing environment. As a key CMC leader, you will drive cross-functional alignment, solve complex development and manufacturing challenges, and partner closely with internal teams and external manufacturers to advance programs. This role is based in our San Francisco headquarters, with an expectation of being onsite at least three days per week.

Requirements

PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, Biology, or a related scientific discipline preferred.
15+ years of biotechnology or pharmaceutical industry experience, including significant leadership experience within biologics process development
Deep expertise in Cell Line Development and Upstream Process Development preferred, with broad experience across drug substance process development for monoclonal antibodies, T-cell engagers, and other large molecule biologics
Demonstrated success advancing biologics programs from early development through commercialization
Extensive experience across process scale-up, characterization, validation, technology transfer, and manufacturing support
Strong experience leading development and manufacturing activities within a highly outsourced CDMO environment
Strong understanding of CMC development, regulatory submissions, and global health authority interactions
Proven ability to build and develop high-performing teams and scientific leaders

Responsibilities

Lead the global Drug Substance Process Development and MSAT organization, fostering scientific excellence, accountability, and collaboration
Define and execute drug substance strategies across the product lifecycle, including process development, scale-up, characterization, validation, technology transfer, and lifecycle management
Set the long-term Drug Substance development strategy to create innovative solutions for developing efficient, robust and cost-effective processes for Mabs and masked T-cell engagers to support the current portfolio and future pipeline
Oversee manufacturing support and process performance across our external manufacturing network
Work closely with other TechOps and Quality functions to participate in comprehensive CMC development of Vir Bio pipeline molecules
Serve as a key CMC leader across development programs, driving alignment and execution against scientific, technical, and business objective
Lead technology transfers to CDMOs and Vir Bio’s internal pilot plant, proactively managing technical and operational risk
Build strong partnerships with external development and manufacturing organizations
Represent Vir in interactions with FDA, EMA, and other global health authorities, including regulatory submissions, inspections, and agency responses
Partner with executive leadership on portfolio planning, organizational design, resource prioritization, and investment decisions
Develop scientific leaders and organizational capabilities to support pipeline growth
Drive operational excellence, continuous improvement, and scalable development practices across the organization