Vice President, Portfolio Sales and Field Team

Revolution Medicines

8d • $294,000 - $367,000 • Remote

About The Position

Revolution Medicines is a global, commercial-stage oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.
Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
The Opportunity:
The Vice President, Oncology Sales will lead the design, build, and execution of a high-performing, national oncology sales organization supporting Revolution Medicines products/services to the oncology community. Reporting to the SVP of US Marketing & Field, the VP will be responsible for creating and scaling a best-in-class sales organization, ensuring successful product launches, and driving sustained revenue growth. This leader will combine strategic vision with operational rigor, leveraging deep oncology expertise and cross-functional collaboration to position the organization for long-term success.

Requirements

• Bachelor’s degree required; advanced degree (MBA, PharmD, PhD) preferred.
• 25+ years of biopharmaceutical industry experience, including significant oncology leadership.
• Proven track record of building and scaling sales organizations, preferably in small-to-mid-size biotech environments.
• Demonstrated success leading oncology product launches, including oral oncolytics.
• Prior leadership of second-line leaders (e.g., regional directors managing managers and reps).
• Deep expertise in oncology market dynamics, including GI, NSCLC preferred.
• Strong strategic, analytical, and operational leadership capabilities.
• Experience working in highly cross-functional, matrixed organizations.
• Willingness to travel (~50%).

Nice To Haves

• Experience in NSCLC and/or GI oncology markets.
• Broad understanding of commercial functions including market access, marketing, training, and sales operations.
• Demonstrated ability to influence at executive levels internally and externally.
• Strong project management and organizational skills, with the ability to manage multiple priorities.
• Proven ability to build culture and lead through change in high-growth environments.

Responsibilities

• Architect and execute the build-out of a national portfolio oncology sales organization, including hiring, onboarding, and development of regional leaders, account directors, and sales representatives.
• This will include nurse educator and other field facing roles or functions including sales operations and training.
• Establish organizational structure, roles, and deployment strategy aligned to brand objectives and market dynamics.
• Foster a high-performance culture grounded in accountability, collaboration, innovation, and patient-centricity.
• Develop leadership bench strength through coaching, succession planning, and talent development initiatives.
• Define and execute the national sales strategy across oncology indications, ensuring alignment with corporate objectives and brand strategies.
• Lead all aspects of product launch readiness and execution, including field deployment, targeting, messaging alignment, and performance tracking.
• Partner with Commercial Leadership Team to shape enterprise-wide strategy, providing field insights and actionable recommendations.
• Drive achievement of all revenue and performance targets, ensuring consistent delivery against quarterly and annual goals.
• Oversee development and execution of key commercial levers including: Forecasting and demand planning, Incentive compensation design, Territory alignment and targeting, Performance analytics and reporting, Training and capability development programs.
• Ensure disciplined execution of business plans and continuous optimization based on market feedback and data insights.
• Lead strategy and executive engagement for top national accounts, including major health systems, IDNs, oncology networks, and GPOs.
• Oversee development and execution of strategic account plans that drive access, adoption, and long-term partnerships.
• Serve as a senior external representative of the company with key stakeholders and decision-makers.
• Partner closely with Marketing, Market Access, Medical Affairs, Commercial Operations, and Training to ensure aligned execution.
• Lead cross-functional initiatives to address business challenges, optimize launch performance, and enhance customer experience.
• Act as the “voice of the field” to inform brand strategy, pipeline planning, and organizational priorities.
• Shape clinical development planning and prioritization.
• Ensure all field activities adhere to regulatory, legal, and compliance standards.
• Model and reinforce ethical leadership and decision-making across the organization.

Benefits

• competitive cash compensation
• robust equity awards
• strong benefits
• significant learning and development opportunities
• eligibility to earn commissions/bonus based on company and/or individual performance

What This Job Offers

• Job Type: Full-time
• Career Level: Executive