Vice President, Pharmacovigilance

Deciphera Pharmaceuticals • Waltham, MA

2d • $335,000 - $460,000 • Remote

About The Position

We are seeking a strategic and accomplished Vice President, Pharmacovigilance to lead Deciphera’s global drug safety and pharmacovigilance function. This executive leader will be accountable for patient safety, regulatory compliance, and proactive benefit-risk assessment across investigational and marketed products. The VP will set the vision for safety governance, product safety strategy, risk management, regulatory safety support, and pharmacovigilance operations while partnering closely across Clinical Development, Regulatory Affairs, Medical Affairs, Quality, Commercial, Technical Operations, and other key functions.

Requirements

• MD, DO, PharmD, PhD, or equivalent advanced scientific or healthcare degree.
• 15+ years of progressive experience in pharmacovigilance, clinical safety, drug safety, or drug development within the biotechnology or pharmaceutical industry.
• 8+ years of leadership experience managing global pharmacovigilance, clinical safety, or patient safety organizations.
• Demonstrated experience supporting products across clinical development and commercialization.
• Deep understanding of global pharmacovigilance regulations, guidelines, and industry best practices, including FDA, EMA, ICH, GCP, and other applicable requirements.
• Experience with safety governance, benefit-risk assessment, signal detection, risk management, safety reporting, and inspection readiness.
• Track record of successful health authority interactions, regulatory inspections, audits, and cross-functional safety leadership.
• Strong strategic leadership, communication, decision-making, and stakeholder management skills.

Nice To Haves

• Oncology experience strongly preferred.
• Experience supporting small molecule therapeutics.
• Prior experience leading pharmacovigilance activities for commercial-stage products.
• Experience working in a global, outsourced operating model utilizing CROs and external pharmacovigilance vendors.
• Demonstrated success building, scaling, and evolving pharmacovigilance organizations, systems, and operating models.
• Experience supporting regulatory submissions, product launches, and post-marketing safety activities in multiple global markets.
• Strong business acumen with the ability to align safety strategy with corporate objectives.

Responsibilities

• Develop and execute the global pharmacovigilance strategy in alignment with corporate objectives, regulatory requirements, and Deciphera’s commitment to patient safety.
• Provide executive leadership for benefit-risk evaluation, safety governance, safety surveillance, signal management, and risk management across investigational and marketed products.
• Serve as a senior safety advisor to executive leadership and represent Pharmacovigilance in governance committees, leadership forums, and interactions with health authorities.
• Ensure global pharmacovigilance activities are compliant, inspection-ready, scientifically rigorous, and aligned with applicable regulatory requirements, GCP standards, and internal quality systems.
• Establish and evolve scalable pharmacovigilance systems, processes, quality frameworks, vendor partnerships, and operational capabilities to support a growing global portfolio.
• Build, develop, and lead a high-performing pharmacovigilance organization while fostering a culture of scientific excellence, accountability, collaboration, and patient-focused decision making.

Benefits

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Education Level: Ph.D. or professional degree