Vice President, Head of Data Science & Biostatistics
About The Position
Solid Biosciences is seeking a Vice President, Head of Data Science & Biostatistics to provide strategic and operational leadership for data sciences across late-stage clinical development for multiple Phase 3 gene trials as well as early stage clinical studies focused on neuromuscular and cardiac diseases. This role will partner cross-functionally to ensure the integrity, rigor, and translational value of clinical data, enabling decisive regulatory, clinical, and commercial outcomes. This leader will oversee a team of biostatisticians and serve as the accountable executive for statistical strategy, data science innovation, and biostatistics integration across clinical programs. The VP will play a critical role in advancing registrational studies, regulatory filings, and lifecycle management while building scalable capabilities to support commercialization and post-marketing evidence generation. Reporting to the Chief Medical Officer, the role will be flexible based on location and alignment with the CMO.
Requirements
- Master’s degree of higher in Biostatistics, Statistics, or related field.
- 15+ years in biotech/pharma with late-stage clinical experience.
- Proven success supporting regulatory submissions and FDA/EMA interactions.
- Expertise in clinical trial design, statistical methods, and regulatory standards.
- Strong leadership and communication skills.
Nice To Haves
- Experience in gene therapy, rare disease, or neuromuscular/cardiac indications preferred.
Responsibilities
- Define and execute the company’s data science, biostatistics, and biostatistics strategy aligned to Phase 3 execution and regulatory success.
- Serve as a core member of the Clinical Leadership Team and partner with the CMO on clinical strategy.
- Lead statistical design and execution of Phase 3 trials, including SAPs, protocols, and interim analyses.
- Ensure compliance with GCP, ICH guidelines, and regulatory expectations.
- Support regulatory submissions (BLA/MAA) and health authority interactions.
- Integrate biost and multi-omics data into clinical development.
- Advance modern data science approaches, including modeling and AI/ML where appropriate.
- Lead and develop a team of 4 biostatisticians.
- Lead and develop a team of 3 database managers
- Manage CROs and external partners.
- Partner cross-functionally across Clinical, Regulatory, Medical Affairs, and Commercial.
Benefits
- Competitive Health and Dental programs with flexible plan offerings, including FSA and HSA programs
- 401(k) program participation with competitive company matched contributions
- Eligibility to participate in Solid’s Employee Stock Purchase Plan
- Mobile phone subsidy for eligible employees
- Tuition Reimbursement
- Vision Coverage
- Life Insurance
- Voluntary Pet Insurance
- Employee Discount Program on Travel, Entertainment, and Services
- Daily Subsidized Lunch Delivery (onsite @ Hood Park)
- Free Onsite Full-Service Gym (onsite @ Hood Park)
- Employee Parking (onsite @ Hood Park)
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What This Job Offers
Job Type
Full-time
Career Level
Executive
