Vice President, Global Commercial Strategy Lead, Inflammation & Immunology + Rare Disease

Pfizer • New York City, NY

3d • Onsite

About The Position

The Vice President, Global Commercial Strategy Lead for Inflammation & Immunology (I&I) and Rare Disease is responsible for driving long-range commercial strategy, portfolio management, and commercial success across both pipeline and inline brands. This role serves as the single, authoritative commercial voice to R&D, Business Development, and US & International Commercial Regions, establishing clear commercial leadership to improve portfolio decision-making and trade-offs, ensure optimal launch and brand marketing strategies, and maximize global patient impact and enterprise value realization for our I&I and Rare Disease portfolio. Reporting to the Global Commercial Strategy Lead, this leader shapes decisions on I&I and Rare Disease portfolio prioritization, lifecycle value optimization, and global marketing strategy. The position partners closely with R&D, Medical Affairs, Global Access & Value, and Regional Commercial teams to deliver breakthrough therapies addressing autoimmune, inflammatory, and rare diseases. Success in this role requires a senior commercial strategist who combines scientific depth with decisive enterprise leadership. This leader must confidently engage in complex scientific and clinical discussions, synthesize insights across R&D, Access, and Commercial teams, and convert them into clear portfolio priorities and differentiated global strategies. With full accountability for value creation, the role requires strong P&L acumen and the ability to make disciplined trade-offs that optimize lifecycle value, launch success, and long-term portfolio performance. The I&I and Rare Disease portfolio represents significant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes to generate highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally with 22 ongoing clinical studies underway to significantly expand our product portfolio over the next several years.

Requirements

• Bachelor's degree in Life Sciences, Business, Marketing, or related field required.
• Minimum 15+ years of successful, progressive marketing, commercial, and/or development experience in pharmaceutical or biotechnology industry.
• Minimum 8-10 years in commercial leadership roles including Global/US/International marketing, commercial development/strategy.
• Experience in both pipeline (pre-launch) and inline (post-launch) brand management spanning early development through commercialization.
• Brand management experience developing product strategies, positioning programs, and go-to-market plans.
• Product launch experience including global launch planning and execution.
• Portfolio management and strategic planning expertise across multiple therapeutic areas and development stages.
• Demonstrated ability to influence complex development decisions and engage deeply in scientific dialogue.
• Second-line leadership experience with accountability for developing and managing senior leaders.
• Demonstrated ability to lead cross-functional teams and influencing without direct authority while managing complex stakeholder environments.
• Track record of building and developing high-performing teams.
• Strategic thinking and vision-setting capabilities with ability to translate into executable plans.
• Financial and business acumen including forecasting, business case development, and investment prioritization.
• Understanding of market access dynamics, payer strategies, and value demonstration.
• Strong enterprise mindset, with proven P&L leadership capability and executive presence.
• Comfort working in a fast-paced environment and making complex decisions quickly.
• Ability to leverage AI models, synthesize and analyze complex data, and understand trends and mathematical calculations.
• Candidates must be authorized to be employed in the U.S. by any employer.
• This position requires permanent work authorization in the United States.

Nice To Haves

• MBA or other advanced degree (PhD, MD, PharmD) strongly preferred.

Responsibilities

• Develop and execute comprehensive long-range commercial and marketing strategies for I&I and Rare Disease portfolios, encompassing pipeline assets from early development to in-line assets through commercial maturity.
• Serve as single, authoritative commercial voice to R&D, Commercial Regions, and Business Development strengthening commercial input from early development through launch via participation in I&I Strategy Governance Team to influence clinical development plans and investment decisions.
• Lead development of business cases for new product launches and lifecycle management investments.
• Lead integrated global launch and marketing strategies coordinating cross-functional teams across R&D, Commercial Regions, Medical, Regulatory, Market Access, and Supply.
• Drive new product and indication launch readiness planning including market development activities, brand positioning, competitive assessments, and HCP/patient unmet need analysis.
• Own commercial asset lifecycle strategy for I&I and Rare Disease including implications of new indications and competitive dynamics.
• Raise the bar on marketing impact, quality, and brand performance by establishing consistently higher, impact-driven standards for strategic outputs and creative excellence.
• Lead proactive market shaping in moments that matter, anticipating and addressing threats with pre-emptive strategies.
• Steer Commercial prioritization of evidence generation strategies across lifecycle and Regions to enable sharper cross-functional decisions and portfolio value maximization.
• Provide global strategic direction for in-line assets while enabling regional adaptation and tactical alignment.
• Own global brand strategy, launch plans, lifecycle management, and core content packages.
• Partner with Global Access & Value (GAV) teams to develop pricing, contracting, and market access strategies that maximize global value of our portfolio.
• Build and lead high-performing Global Commercial Strategy organization of 50+ highly engaged colleagues.
• Embed culture of cross-functional collaboration ensuring coordinated internal and external stakeholder engagement.
• Develop future commercial leaders with the capability to operate across full span of commercial development, launch, and in-line commercialization.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive