Vice President, Clinical Trial Operations National Center for Clinical Trials

Advocate Health and Hospitals Corporation • Charlotte, NC

31d • $132 - $211 • Remote

About The Position

Provides strategic and operational leadership for the Advocate Health National Center for Clinical Trials (NCCT), ensuring the efficient, compliant, and high-quality execution of clinical trials across a national footprint of hospitals and care sites. This role is pivotal in advancing NCCT’s mission to make clinical trials a routine part of patient care, harmonizing processes across regions and functions, and leveraging technology to deliver operational excellence. Leads enterprise-wide integration of trial operations into clinical workflows, standardize procedures, and foster collaboration with internal and external stakeholders to position NCCT as a national leader in clinical research. Remote based position with monthly travel expectations.

Requirements

• Bachelor’s degree
• At least 10 years in clinical research operations with at least 7 years in senior leadership roles overseeing multi-site or enterprise-level programs
• Deep knowledge of FDA regulations, ICH-GCP, and clinical trial processes; experience with IRB administration and compliance.
• Familiarity with CTMS, EHR integrations, and advanced recruitment technologies.
• Proven ability to lead large teams, manage complex portfolios, and drive organizational change in a matrixed environment.
• Exceptional interpersonal skills to engage diverse stakeholders and foster cross-functional alignment.
• Strong analytical, decision-making, and financial management skills; commitment to operational excellence and patient-centered research.

Responsibilities

• Translate NCCT’s vision into operational strategies and execution plans that embed clinical trials into routine care across Advocate Health’s network.
• Establish and support NCCT-designated trial sites across Advocate Health regions, ensuring readiness, staff training, and operational capability.
• Champion strategies to expand patient access and diversity in trials, leveraging centralized recruitment programs and community engagement.
• Drive adoption of emerging methodologies such as decentralized trials and telehealth integrations and benchmark NCCT operations against leading industry standards.
• Represent NCCT in externally facing engagements, including client meetings, industry conferences, and professional forums, to showcase capabilities and strengthen strategic partnerships.
• Direct end-to-end trial operations, including site activation, recruitment, execution, and close-out, ensuring adherence to timelines, budgets, and regulatory standards.
• Develop and implement SOPs, policies, and best practices to harmonize trial conduct across all sites under a single IRB and unified infrastructure.
• Oversee adoption of enterprise-wide tools such as CTMS, EHR, and AI-driven recruitment platforms to streamline workflows and enhance patient engagement.
• Define and monitor KPIs for trial operations and use data-driven insights to identify bottlenecks and implement continuous improvement initiatives.
• Manage operational resources effectively, including forecasting needs, allocating staff and budgets, and maintaining ownership for resource planning to support current and future trial demands.
• Oversee the operations of a contact center with both inbound and outbound capabilities to engage clinical trial participants, ensuring timely communication, responsiveness, and a positive participant experience.
• Manage staff responsible for centralized recruitment and retention of clinical trial participants, ensuring effective strategies, timely enrollment, and sustained engagement throughout the study.
• Leverage technology and analytics to monitor and optimize recruitment and retention performance, using real-time dashboards and data insights to drive continuous improvement in participant engagement.
• Manage staff responsible for project management and study oversight.
• Manage staff performing duties related to regulatory document maintenance, submissions to the IRB, and ensure the Investigator Site File for each trial remains audit-ready at all times.
• Serve as the primary operational liaison to sponsors, CROs, investigators, and internal leaders, ensuring strong relationships and delivery on contractual obligations.
• Align closely with the Business Development and Sales function to ensure operational delivery excellence for awarded work and actively support pre-sales efforts to secure new partnerships and trial opportunities.
• Collaborate tightly with Regulatory, Quality, and Compliance function to ensure data integrity, patient safety, and adherence to all applicable standards and guidelines.
• Work closely with Finance and Legal functions on budget and contract development, financial reconciliation, and compliance with sponsor and institutional requirements.

Benefits

• Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more – so you can live fully at and away from work, including:
• Compensation Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training Premium pay such as shift, on call, and more based on a teammate's job Incentive pay for select positions Opportunity for annual increases based on performance
• Benefits and more Paid Time Off programs Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability Flexible Spending Accounts for eligible health care and dependent care expenses Family benefits such as adoption assistance and paid parental leave Defined contribution retirement plans with employer match and other financial wellness programs Educational Assistance Program

What This Job Offers

• Job Type: Full-time
• Career Level: Executive
• Number of Employees: 5,001-10,000 employees