US Medical Head, COPD Biologics

AstraZeneca•Wilmington, DE

3d•Hybrid

About The Position

This role sits at the heart of AstraZeneca's mission, combining scientific depth with strategic leadership to advance care in chronic respiratory disease. As the US Medical Head, COPD Biologics, this position owns the medical strategy and execution for a novel Interleukin-33 targeting monoclonal antibody, crafting both product and disease area direction across the full lifecycle. This leader will guide a high-performing team, drive launches, and influence how evidence, access and clinical practice come together to transform outcomes for patients living with COPD and severe lower respiratory tract disease.

Requirements

Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
A Minimum of 7 years of experience in the pharmaceutical industry, ideally in Medical Affairs, working at the country and global/regional level
Medical/clinical/scientific expertise in Respiratory Disease
Experienced team leader, with a track record of establishing high performance teams
Demonstrated track record delivering results in a sophisticated matrix environment, building capabilities, and leading impactful medical initiatives.
Experience launching a new product
US Regulatory Strategy Knowledge including product approval, label requirements/ negotiation
Consistent track record to collaborate and build internal and external networks
Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment

Nice To Haves

Leadership experience in US Medical Affairs for respiratory biologics or other specialty therapeutics.
Direct involvement in major US product launches in COPD or related respiratory indications.
Experience crafting or overseeing real-world evidence programs passionate about payer needs and healthcare system impact.
Background working closely with field medical teams and external authorities to develop standards of care.
Track record influencing cross-functional investment decisions using medical insights and data.

Responsibilities

Lead and grow the COPD Biologics US medical team, setting clear vision, priorities and standards for excellence in disease area and brand strategy and execution.
Develop and deliver coordinated medical strategies and plans for COPD Biologics and related indications, ensuring alignment with global medical, US commercial and market access partners.
Develop and implement Transforming Healthcare initiatives that shape the biologics market in COPD Biologics, severe LRTD and adjacent areas, using evidence and insight to influence clinical practice and care pathways.
Own disease area and brand medical budgets and resource planning, ensuring optimal allocation to high-impact activities across the lifecycle.
Co-lead the COPD Biologics Core Value Team with Commercial and Market Access leaders, connecting strategy, science, access and execution to deliver a cohesive launch plan.
Continuously assess and communicate the competitive landscape, translating insights into differentiated positioning and tactical plans.
Act as the primary US medical point of contact for the Global Product Team (GPT), providing strategic input on lifecycle management, phase IV strategy and study design.
Partner with evidence generation teams to define and execute real-world evidence programs that address US clinical, payer and policy needs.
Build and sustain positive relationships with external authorities, professional societies, patient groups and key internal stakeholders to inform strategy and amplify scientific leadership.
Serve as a medical spokesperson for COPD biologics in response to media inquiries when required, ensuring accurate, balanced and compliant communication.
Coach, mentor and develop direct reports, actively leading succession, talent development and engagement within the team.
Nurture a culture that values scientific rigor, teamwork, innovation and recognition, while maintaining full compliance with AstraZeneca policies and external regulations.

Benefits

AstraZeneca offers an environment where medical leaders sit at the intersection of science and real-world practice, using evidence to influence how care is delivered today and tomorrow.
Work alongside experts who embrace change because it sparks innovation, from bold real-world studies to pioneering launches that shift treatment paradigms in respiratory disease.
Collaboration across research, medical and commercial functions is embedded in how things get done here, opening doors to new ideas, broader networks and continuous development without borders.
Every study designed, every partnership built and every insight translated into practice contributes directly to better outcomes for patients and fuels the next wave of scientific progress.
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics.
If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company.
We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases.
At AstraZeneca, we’re dedicated to being a Great Place to Work.
Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit.
To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges.
There is no better place to make a difference in medicine, patients, and society.
An inclusive culture where you will connect different thinking to generate new and valuable opportunities.
Where you will find a commitment to lifelong learning, growth and development for all.
Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.
Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking.
We’re curious about science and the advancement of knowledge.
We find creative ways to approach new challenges.
We’re driven to make the right choices and be accountable for our actions.
As an organisation centred around what makes us human, we put a big focus on people.
Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab.
Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential.
Here, you’ll do work that has the potential to change your life and improve countless others.
And, together with your team, you’ll shape a culture that unites and inspires us every day.
This is your life at AstraZeneca.