US Medical Early Asset Director– Insights

AstraZeneca•Wilmington, DE

3d•Hybrid

About The Position

This role is crucial in leveraging scientific capabilities to positively impact patients' lives. The US Medical Early Asset Director – Insights will be responsible for developing ambitious US medical strategies for the early pipeline. This position offers an opportunity to influence across a complex matrix system, ensuring US needs are integrated into global development plans. The role focuses on insight generation and decision analytics for pipeline assets from late discovery through Phase 2, translating ambiguity into clear, evidence-based recommendations by integrating secondary analytics, custom market research, competitive intelligence, epidemiology, and early forecasting. The individual will partner closely with Global/US Commercial, Medical, Clinical Development, Market Access, HEOR, and Finance to shape target product profiles, influence trial design, test differentiation hypotheses, and inform investment decisions at stage gates.

Requirements

Bachelor’s degree required
5+ years in pharma/biotech or consulting focused on market insights, new product planning, or early commercial strategy
US market experience required
Demonstrated impact shaping TPPs, influencing clinical/evidence plans, and informing investment decisions via robust insights and analytics.
Effective at partnering with Clinical, Medical, Market Access/HEOR, and Finance; leads without authority in matrixed teams.

Nice To Haves

Advanced degree preferred (MBA, MPH, MS in Market Research/Statistics, PharmD, or related)
Early development experience (Phase 1–2) strongly preferred
Hands-on experience with qualitative and quantitative methods (e.g., conjoint/DCE, segmentation, ATU/DTU, message testing) and vendor oversight.
Proficiency with forecasting basics, epidemiology inputs, claims/EMR analytics, and triangulation across data sources; comfort with uncertainty and sensitivity testing.
Ability to translate competitor clinical and access moves into implications for positioning and evidence.
Clear, concise communicator who turns complex data into actionable recommendations for senior stakeholders and governance.
Working knowledge of analytics and visualization tools (e.g., Excel, PowerPoint; familiarity with data platforms/BI tools is a plus).
Practical experience using AI/ML-enabled tools for insights work (e.g., NLP for unstructured text, predictive modeling, synthetic respondent methods, automated coding of qual, prompt engineering for analysis/synthesis) with an understanding of data privacy, bias, and validation best practices.

Responsibilities

Define the US insights learning plan across asset stages, prioritizing critical unknowns and decision points, and mapping research/analytics to governance milestones.
Pressure-test TPP elements (endpoints, attributes, device/format, administration setting, line of therapy, subsegments) via research and rapid experiments; recommend trade-offs to maximize US value.
Design and lead payer/HCP/patient qualitative and quantitative studies (concept tests, message/value testing, conjoint/DTU, ethnography, discrete choice, max-diff) to refine positioning and evidence needs.
Synthesize syndicated data, claims/EMR analyses, epidemiology, treatment paradigms, and policy trends to size opportunities, refine segmentation, and anticipate adoption barriers.
Maintain dynamic competitor profiles, trial readouts, label trajectories, and access precedents; run competitor simulations and implications for differentiation and timing.
Build and refine early demand/adoption forecasts, market maps, and scenario trees; partner with Finance on rNPV and sensitivity analyses that reflect uncertainty and key inflection points.
Translate insight into guidance on endpoints, comparators, PROs, inclusion/exclusion, and RWE priorities that support future US adoption, labeling, and access.
Identify priority segments (HCPs, treatment centers, IDNs, payers, patient pathways) and define decision drivers across the care continuum to inform early brand strategy and initial field teams' structure.
Co-create early value narratives and differentiation hypotheses; test resonance and credibility with customers and iterate with Medical/HEOR and Market Access.
Stand up lightweight experiments (concept sprints, ad boards, rapid quant) to answer time-sensitive questions ahead of governance gates and external catalysts.
Craft clear, concise readouts and recommendations for asset teams and governance; ensure traceability from insight to decision and document assumptions/risks.
Select and manage research/analytics vendors; ensure methodological rigor, compliance, and on-time, on-budget delivery.
Conduct research and external engagements in line with US regulations and company policies for pre-approval communications and data privacy.

Benefits

AstraZeneca is dedicated to being a Great Place to Work.
Empowerment to push the boundaries of science, challenge convention and unleash entrepreneurial spirit.
Embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges.
An inclusive culture where you will connect different thinking to generate new and valuable opportunities.
Commitment to lifelong learning, growth and development for all.
An inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients.
Opportunity to wake up excited about your day at the office, in the field, or in the lab.
Promise to help you realize the full breadth of your potential.
Work that has the potential to change your life and improve countless others.
Shape a culture that unites and inspires us every day.