US HEVA Dupixent Team Lead

Sanofi•Cambridge, MA

13h•Hybrid

About The Position

Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. Sanofi's Purpose and Mission: Sanofi is an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people's lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time. Dupixent Purpose: Dupixent is a significant portfolio for Sanofi. Designed to target underlying drivers of chronic inflammatory disease, Dupixent has received regulatory approvals in more than 60 countries across multiple indications, including atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, prurigo nodularis, chronic spontaneous urticaria, chronic obstructive pulmonary disease, and bullous pemphigoid, spanning diverse age populations. More than one million patients are currently treated with Dupixent globally. Supported by an extensive clinical development program of more than 60 studies in over 10,000 patients, Sanofi and Regeneron are studying dupilumab in a broad range of diseases driven by type 2 inflammation or other allergic processes in phase 3 studies. As the portfolio continues to expand, Dupixent is redefining standards of care, broadening patient impact, and delivering sustained value across healthcare systems worldwide. HEVA Vision, Mission, and Values: We are one bold HEOR team leveraging innovative HEOR to transform patient care and access. As HEOR experts, we lead the generation and dissemination of robust, business-relevant evidence to demonstrate value and drive access to medicines. The HEVA organization is driven by five core values that define how we work and deliver impact. We operate as One Team, partnering without boundaries while pursuing a Bold Purpose through ambitious, measurable goals. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Requirements

Minimum 10 years of experience in health economics, outcomes research, or a related field
Advanced degree (PhD, PharmD, Masters or equivalent) in health economics, epidemiology, public health, economics, or related field required
Demonstrated expertise in health economic modeling, real-world evidence generation, and outcomes research methodologies
Deep expertise in US healthcare, payer dynamics, and policy, with a track record of translating evidence into strategic impact
Proven track record of successful market access and reimbursement support through HEVA evidence and ability to influence decision-making at the highest levels of the organization using HEVA developed insights and evidence
Strong command of US evidence dissemination (HCEI/PIE, reactive/proactive, CFL, AMCP dossiers)
Exceptional leadership skills with demonstrated ability to inspire, motivate, and develop high-performing teams
Strong change management capabilities and experience leading organizational transformation initiatives
Proven ability to influence and collaborate effectively across all organizational levels and functions
Extensive experience in immunology therapeutic areas required, including deep understanding of disease pathophysiology, treatment paradigms, and market dynamics
Strong written and verbal communication skills in English
Ability to synthesize complex data into clear, actionable insights and strategic recommendations

Responsibilities

This role leads US HEVA strategy and execution for Dupixent across indications, leading a team in ensuring the generation, translation, and dissemination of high-quality, decision-relevant evidence to impact access in the United States.
Drive measurable business impact through strategic US HEVA initiatives that directly support US commercial objectives and US market access goals compliantly and efficiently
Develop and execute comprehensive US HEVA strategies that maximize product value propositions and competitive positioning, ensuring alignment with Global HEVA strategy
Partner with commercial teams to translate HEVA insights into actionable business strategies
Drive development of business-relevant US research agendas and strategies through cross-functional input and alignment
Provide exceptional leadership to the US Dupixent HEVA team, fostering a culture of excellence, innovation, and impact driven performance
Mentor and develop team members to build world-class HEVA capabilities within the organization
Drive organizational change and process improvements to enhance team effectiveness and business impact
Represent HEVA with the US Dupixent Franchise Leadership Team
Build and maintain strong relationships with the cross functional teams to ensure pricing and access decisions and brand strategies are supported with demonstratable value of assets per robust evidence packages including real world evidence
Align closely with the Global HEVA team to ensure inclusion of US insights into global strategic plans and coordinate evidence generation, modelling, and evidence synthesis activities
Deliver compelling presentations to senior leadership, including C-suite executives and US leadership teams
Communicate complex health economics concepts and strategic recommendations to senior stakeholders with clarity and impact
Influence key business decisions through data-driven insights and strategic HEVA recommendations
Ensure clinical development plans are designed to deliver true differentiation aligned to Sanofi Dupixent portfolio ambitions
Oversee the design, execution, publication, and further dissemination of high-quality health economics and outcomes research studies to ensure the highest quality of evidence is delivered to support business objectives
Develop comprehensive real-world evidence strategies that support product lifecycle management
Ensure scientific rigor and regulatory compliance across all HEVA research activities
Manage the development of US launch strategies and evidence generation plans, providing strategic HEVA input into Integrated Evidence Generation Plans (IEGPs) to ensure alignment across clinical, real-world evidence, and value demonstration objectives
Across the US HEVA Dupixent team, compliantly lead efforts to further HEOR dissemination, application, and proactive and/or promotional use with US stakeholders (eg, HCEI, PIE, consistent with FDA label)
Partner with Access Strategy teams and US Market Access teams to execute on innovative payer partnership health economics and outcomes research studies and analytics aligned with franchise priorities
Build and maintain strategic relationships with key external stakeholders, including payers, health technology assessment bodies, and academic institutions
Represent Sanofi at major scientific conferences and industry forums
Collaborate with external research partners and key opinion leaders to advance HEVA science
Support external engagement with key external evidence bodies (eg, ICER, PDAB, IRA) on related pricing and access challenges, and evolving reimbursement frameworks
As a leader in Sanofi’s HEVA organization, seek opportunities to actively participate and engage with external professional HEOR societies