Undergraduate Summer Research Intern

Penn State UniversityTallahassee, FL
Onsite

About The Position

The Penn State College of Medicine Department of Molecular and Precision Medicine is seeking applicants for two part-time Undergraduate Summer Interns. These roles provide essential support to ongoing biomedical research, directly contributing to discoveries in autophagy and computational structural biology. Undergraduate researchers gain hands-on experience that advances both their professional development and the lab’s scientific goals.

Requirements

  • Currently enrolled undergraduate student (any year) at an accredited institution
  • Completed at least one college-level biology course (with laboratory preferred)
  • Completed at least one college-level programming course or demonstrated equivalent experience (e.g., Python, R, MATLAB, or similar), required for position B
  • Ability to commit to on-site work at Penn State College of Medicine for the summer term.

Responsibilities

  • Position A – Assists a research associate in preparing recombinant proteins for structural and functional studies of autophagy-related proteins.
  • Position B – Works with an investigator to explore emerging AI-based approaches for computational analysis of NMR data.
  • Protein expression – Assist in transforming, culturing, and inducing bacterial or insect cell lines for recombinant protein production.
  • Protein purification – Perform affinity, ion exchange, or size-exclusion chromatography under supervision.
  • Run SDS-PAGE gels to verify protein purity and integrity.
  • Laboratory recordkeeping – Maintain a detailed lab notebook.
  • Collaborative troubleshooting – Work with the research associate to optimize expression conditions or purification yields as needed.
  • Script development – Write or modify Python scripts to preprocess and analyze NMR spectral data.
  • AI model testing – Assist in applying machine learning tools to NMR spectral interpretation.
  • Results visualization – Generate plots and summary statistics for lab meetings and progress reports.

Benefits

  • The starting rate for this job is $18.00
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