Translational Medicine Associate Director
About The Position
The Translational Science Associate Director is responsible for the implementation of translational and biomarker objectives for cellular, biologics, and small molecule therapies for immune-mediated diseases. This role focuses on ensuring effective collaborations between research and development, establishing strong target-to-disease connections, differentiating AZ therapeutics, and driving translational understanding of clinical trial data. The position involves overseeing translational study strategy and deliverables with CROs and collaborators to support new and ongoing clinical studies, as well as enabling life cycle management and new program strategies at a global product team level. The Associate Director will be recognized as an authority in translational science, working on complex therapeutic projects and scientific problems to provide innovative solutions.
Requirements
- PhD or MD-PhD degree in a relevant field.
- 3 or more years of industry or 5 years combined academic/industry experience in clinical development or translational science.
- Strong knowledge of the pathogenesis of immune mediated disease and the application of cellular, molecular technologies and models to drive program decisions.
- Prior experience in clinical biomarker strategy development and execution including human target validation, target engagement, and molecular differentiation.
- Significant experience managing CROs for translational studies and biomarkers for clinical trials.
- Detailed understanding of translational and clinical research methodology and biostatistics principles.
- Attention to detail, strive to generate high-quality work, and sense of passion and urgency to achieve team and program goals.
- Demonstrated track record in delivering results.
- Outstanding verbal and written communication skills.
- Excellent analytical, problem solving and strategic planning skills.
Nice To Haves
- Degree or training in Immunology preferred.
- Experience in clinical biomarker development of T-cell therapy and/or other advanced therapeutic modalities in house or with CROs.
- Experience in the authoring of relevant sections of regulatory documents.
- Understanding of the full drug development process, with experience across phases of therapeutic development and studies.
- Understanding of FDA, EMA, MHRA and ICH GCP guidelines as they pertain to translational strategy.
Responsibilities
- Implementation of translational and biomarker objectives for cellular, biologics, and small molecule therapies for immune-mediated diseases.
- Ensuring effective collaborations between research and development.
- Establishing strong target-to-disease connections.
- Differentiating AZ therapeutics.
- Driving translational understanding of clinical trial data.
- Overseeing translational study strategy and deliverables with CROs and collaborators to support new and ongoing clinical studies.
- Enabling life cycle management strategy and new program strategies as a global product team level translational lead.
- Providing solutions to complex therapeutic projects and scientific problems.
- Contributing to and leading complex projects.
- Leading translational strategy that shapes pivotal decisions and brings the next generation of B-cell therapies to patients faster.
Benefits
- Qualified retirement programs
- Paid time off (i.e., vacation, holiday, and leaves)
- Health coverage
- Dental coverage
- Vision coverage
- Opportunity to receive short-term incentive bonuses
- Equity-based awards for salaried roles
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
