TPRM Workflow & Risk Orchestration Manager

Vertex Pharmaceuticals•Boston, MA

2d•Hybrid

About The Position

Vertex is seeking a Manager, TPRM Workflow & Risk Orchestration to join the Global Sourcing & Procurement organization within the Source-to-Pay (S2P) Center of Excellence. This role is responsible for designing and embedding third-party risk management (TPRM) into the end-to-end S2P lifecycle through workflow orchestration, lifecycle triggers, and execution guardrails. The Manager will ensure that supplier risk identification, assessment, and mitigation are seamlessly integrated across intake, sourcing, contracting, supplier onboarding, and ongoing supplier lifecycle processes. This individual will translate enterprise risk frameworks into practical, scalable workflows that support compliant execution while preserving speed, usability, and a strong internal customer experience. This is a highly cross-functional individual contributor role with significant influence across Sourcing, Legal, Risk, Compliance, Procurement Operations, Analytics, and Digital/IT. The role owns workflow design and execution enablement, while partnering with stakeholders who manage enterprise risk policy and core technology platforms.

Requirements

Bachelor’s degree required; advanced degree or relevant certifications preferred
6–8+ years of experience in procurement, third-party risk management, sourcing, contracting, vendor master, supplier onboarding, or process design roles
Strong understanding of supplier risk management frameworks and procurement lifecycle processes
Demonstrated experience designing, improving, or operationalizing cross-functional workflows and business processes
Experience working in vendor master, supplier onboarding, procurement operations, or other data-driven process environments
Strong understanding of how supplier data quality and governance impact downstream risk management, compliance, and workflow automation
Proven ability to collaborate across functions and influence stakeholders without direct authority
Strong analytical, organizational, and problem-solving skills with attention to detail
Third-party risk management (TPRM) workflow design and orchestration
Source-to-Pay (S2P), Source-to-Contract (S2C), and supplier lifecycle process knowledge
Supplier onboarding and vendor master data process design
Risk classification, segmentation, and lifecycle trigger models
Business process mapping, workflow design, and control integration
Data governance, validation rules, and approval workflow design
System enablement and business requirements translation
User acceptance testing (UAT), release support, and post-go-live stabilization
KPI development, dashboard requirements, and performance reporting
Cross-functional process integration across Procurement, Legal, Risk, Compliance, and Digital/IT

Nice To Haves

Experience operating within a Center of Excellence (COE) or center-led procurement model
Familiarity with TPRM tools such as ProcessUnity or similar platforms
Familiarity with contract lifecycle management (CLM) tools such as Icertis
Experience with orchestration, intake, or guided buying tools
Experience in highly regulated environments requiring strong controls, auditability, and compliance
Hands-on experience with supplier master data, onboarding workflows, or vendor management processes in a Procure-to-Pay or shared services environment
Exposure to workflow automation, lifecycle triggers, and scalable control design
Experience partnering with Digital/IT teams to translate business needs into system-enabled solutions

Responsibilities

Design, implement, and maintain end-to-end TPRM workflows aligned to key supplier lifecycle events, including onboarding, contract initiation, renewal, and ongoing monitoring
Embed risk assessment, escalation, review, and remediation steps into S2P workflows to support consistent and audit-ready execution
Balance strong risk coverage with operational efficiency and a user-friendly experience
Define and operationalize trigger-based models that initiate risk assessments based on supplier criticality, geography, service type, and lifecycle events
Integrate TPRM requirements into intake, guided buying, and orchestration tools
Ensure alignment of risk workflows across sourcing, contracting, and supplier management processes
Embed TPRM workflows into supplier onboarding and vendor master data processes so that complete and accurate supplier information triggers the right risk activities
Define required supplier data elements, validation rules, approval flows, and controls that support risk classification, segmentation, and monitoring
Partner with Master Data and Procurement Operations teams to align supplier data processes with TPRM workflow requirements
Identify and resolve data quality gaps that affect risk visibility, compliance, or workflow execution
Translate TPRM workflow and supplier data requirements into system configurations across onboarding, vendor master, and risk assessment tools
Ensure supplier master data structures support effective workflow triggers and downstream risk processes
Support user acceptance testing (UAT), release readiness, and post-go-live stabilization for TPRM-related enhancements
Drive scalable, standardized workflow designs aligned with broader S2P orchestration objectives
Monitor workflow performance, cycle times, control effectiveness, and overall risk coverage
Identify and implement enhancements that reduce process friction and improve compliance
Partner with Analytics teams to define KPIs, dashboards, and reporting requirements for workflow performance and risk visibility
Define clear roles, responsibilities, and handoffs across TPRM, Sourcing, Contracting, Legal, Risk, and Operations teams
Support issue resolution and escalation for complex or high-risk supplier scenarios
Ensure alignment with S2P process standards, governance frameworks, and enterprise orchestration strategy

Benefits

Competitive compensation
Comprehensive health and wellness benefits
Retirement savings programs
Paid time off and company holidays
Professional development and career growth opportunities
Collaborative, mission-driven culture
Hybrid work flexibility for eligible roles
Annual bonus
Annual equity awards
Overtime pay
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
Generous commuting subsidy
Matching charitable donations
401(k)