Technologist II

Precision for Medicine•Houston, TX

8d•$33 - $50

About The Position

The Technologist II (Molecular) works in a laboratory setting, applying a broad range of skills and troubleshooting techniques. The role works with scientists to develop and perform molecular biology assays through development, validation, and execution, and to complete work in a timely manner. The technologist performs assays according to SOPs, supports the development of new procedures and improvement of existing SOPs, and operates in a CLIA environment. The role also trains other staff. The position supports quality control and clinical sample testing, maintenance of reagents and consumables, instrument maintenance and troubleshooting, assay qualification, and laboratory compliance with CLIA, GLP, and GCP standards. It may also involve freezer transfers, report generation, and coordination with QC and entry of locations into the BSI. The role requires flexibility in shift work and may require long hours, evenings, weekends, and holidays.

Requirements

Bachelor’s degree in Life Sciences, Biology, or another related discipline.
More than 2 years of prior related laboratory experience.
Skilled in molecular biology techniques and willing to learn and execute related techniques.
Able to work occasional long hours, evenings, weekends, and holidays.
Team player who is detail-oriented and organized, can work under pressure, and has good oral and written communication skills.
Able to scrutinize data effectively and work well in a group environment.
Strong computational skills; preferably experienced with Word, Excel, and PowerPoint.
Excellent judgment and discretion.
Able to lift and carry 1–15 lbs. and lift up to 50 lbs. overhead with assistance; frequently able to sit, grasp, and use right- or left-hand finger dexterity.
Able to work in a cold freezer environment, with freezer temperatures ranging from -20ºC to -196ºC.
Able to read, write, speak fluently, and comprehend English.
Legally authorized to work in the country of employment without employer sponsorship.

Nice To Haves

Four years of related experience, preferably in an NGS core facility or NGS laboratory.
MB (ASCP) certification.
Wet-lab experience across the entire NGS workflow, from library preparation to sequencing, using Illumina or Ion Torrent.
Experience with qPCR, ddPCR, and NanoString.
Experience extracting DNA and RNA from a variety of sources.
Solid laboratory experience across multiple skill sets.
Understanding of current GLP or CAP/CLIA/ISO standards.
Laboratory documentation experience with regulatory guidelines such as cGMP, cGLP, or ISO, and SOPs.

Responsibilities

Perform molecular biology assays according to SOPs and support development of new procedures and improvement of existing SOPs.
Work with scientists to develop and perform assays, including qualification of assays for new projects.
Learn and execute techniques related to RNA and DNA extraction, qPCR, NGS, and other molecular biology platforms.
Run quality control samples and clinical samples, and generate data.
Maintain stocks of required reagents and consumables.
Perform daily, weekly, and monthly instrument maintenance and troubleshoot as required.
Work with Quality Assurance on documentation and ensure laboratory operations follow CLIA, GLP, and GCP standards.
Train new personnel on project-related assays, daily laboratory work, and SOPs.
Participate in cross-functional process improvement activities.
Contribute to reagent quality control through various tests and writing SOPs.
As needed, complete freezer transfers, generate reports, coordinate with QC, and enter locations into the BSI.
Perform other duties as assigned.