Technical Program Manager, AI Simulation

SandboxAQ

3d • $156,800 - $294,000 • Hybrid

About The Position

SandboxAQ is a high-growth company delivering AI solutions that address some of the world's greatest challenges. The company’s Large Quantitative Models (LQMs) power advances in life sciences, financial services, navigation, cybersecurity, and other sectors. We are a global team that is tech-focused and includes experts in AI, chemistry, cybersecurity, physics, mathematics, medicine, engineering, and other specialties. The company emerged from Alphabet Inc. as an independent, growth capital-backed company in 2022, funded by leading investors and supported by a braintrust of industry leaders. At SandboxAQ, we’ve cultivated an environment that encourages creativity, collaboration, and impact. By investing deeply in our people, we’re building a thriving, global workforce poised to tackle the world's epic challenges. Join us to advance your career in pursuit of an inspiring mission, in a community of like-minded people who value entrepreneurialism, ownership, and transformative impact.

The AI Simulation (AISim) Business Unit is deploying our internal platform and Large Quantitative Models across seven critical semiconductor material verticals. The Operations function is the execution backbone of the business unit, keeping a multi-vertical program on track across science, engineering, partnerships, and reporting.

We are seeking a Technical Program Manager to serve as a cross-functional operational leader across a portfolio of technical programs. In this role, you will establish the operating cadence across teams and functions, drive clear milestone and status communication, surface risks and dependencies early, and build the processes, tools, and playbooks that help the organization scale execution effectively. You will work closely with senior leaders across science, product, engineering, business development, and operations to keep priorities aligned and programs moving.

Requirements

• 8+ years managing complex, multi-workstream technical programs in regulated, high-stakes environments (federal contracts, defense, large enterprise R&D, or similar).
• Demonstrated experience operating against U.S. Government program requirements, including familiarity with milestone reporting, compliance documentation, and contracting cadence.
• Strong technical literacy across AI, scientific computing, or materials/chemistry programs sufficient to challenge schedules, scope, and dependencies credibly with senior scientists and engineers.
• Exceptional executive-level communication; able to translate technical detail for non-technical government and executive audiences and to drive trade-off conversations when scope, time, or budget are at risk.
• Bachelor’s degree in a technical field (engineering, computer science, physical sciences, or related); advanced degree preferred.
• Because this position supports specific U.S. Government contractual requirements, we can only consider US Persons (Permanent Residents or Citizens) at this time.

Nice To Haves

• Direct experience supporting or executing CHIPS Act, BAA, OTA, or similar federally funded R&D programs.
• Familiarity with materials science, semiconductor manufacturing, or computational chemistry program contexts.
• Experience standing up the operating system of a new BU or program office in a high-growth company.
• PMP, PgMP, or equivalent program management certification.

Responsibilities

• Run the cross-vertical operating cadence for Chemical Simulation, including weekly stand-ups, monthly business reviews, and quarterly reporting cycles, ensuring on-time, audit-ready delivery to government stakeholders.
• Own the cross-vertical source of truth for milestones, dependencies, risks, and decisions across the seven Programmatic Areas; surface variance early and drive corrective action with the GM and Vertical Leads.
• Serve as the day-to-day operational interface to government counterparts, translating technical progress into compliance-grade narratives, deliverables, and quarterly updates.
• Coordinate cross-functional execution across Vertical Leads, Platform Engineering, Product, BD, Recruiting, Finance, and Legal/Compliance to unblock teams and protect program timelines.
• Design and operationalize the program management toolkit for Chemical Simulation, including dashboards, decision logs, resourcing models, and reporting templates that scale across verticals and survive leadership transitions.

Benefits

• Competitive base salary commensurate with experience, plus equity and performance-based incentives.
• Comprehensive health, dental, and vision insurance
• 401(k) with company match
• Generous parental leave.
• Flexible hybrid work arrangements
• Generous PTO
• Mentorship
• Dedicated learning budgets to support continued growth.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior