Technical Officer, Cell Culture Scale-Up

National Research Council CanadaMontreal, QC
CA$83,435 - CA$107,838Onsite

About The Position

The NRC is seeking a Technical Officer, Cell Culture Scale-Up to support our Human Health Therapeutics Research Centre. This role is crucial for developing mammalian expression systems and bioprocesses for large-scale production of biologics, including recombinant proteins, viral vectors, and viruses. The successful candidate will provide technical support for experiment design, planning, execution, and analysis, as well as technology transfer of R&D processes. The NRC is recognized as one of Canada’s Top Employers for Young People, a Top Employer in the National Capital Region, and one of Forbes Canada’s Best Employers, fostering a supportive culture of creativity, innovation, and teamwork.

Requirements

  • A minimum of Bachelor’s degree in biochemical/chemical engineering, molecular or cellular biology, microbiology engineering, or a related field.
  • Significant experience in bioprocess development and scale-up with expression systems for the production of recombinant proteins and/or viral vectors and /or viruses for vaccine development.
  • Experience with operating bioreactors in different modes (batch and/or fed-batch and/or perfusion).
  • Experience working in aseptic conditions, preferably with mammalian cells.
  • Experience in working with multidisciplinary teams.
  • Experience with data management, data analysis and data reporting under structured technical report format.
  • Good knowledge of biomanufacturing principles.
  • Good knowledge of bioreactor operation.
  • Significant knowledge of cell biology and cell culture principles and/or fermentation.
  • Knowledge of molecular biology.
  • Knowledge of Excel, Word and Powerpoint Microsoft softwares and data management, data analysis and data reporting under structured technical report format using these softwares.

Nice To Haves

  • A university degree in Bioengineering may be considered an asset.
  • Experience in analytical techniques applied to quantification and characterization of recombinant proteins and/or viral vectors would be an asset.
  • Experience working with suspension cell cultures in flasks or other high-throughput small scale equipment such as mini-bioreactors or deep well plates including experience with typical cell culture instrumentation used for off-line and on-line measurements of operating parameters and cell culture metabolites would be an asset.
  • Experience in cell culture media development and optimization of cell culture processes operating conditions would be an asset.

Responsibilities

  • Provide technical support services in the design, planning, preparation, conduct and analysis of various experiments and/or tests.
  • Support technology transfer of R&D processes.
  • Interact with different R&D teams and functions towards the development of mammalian expression systems and bioprocesses for the large-scale production of biologics including recombinant proteins, viral vectors and viruses.

Benefits

  • Robust pension plan
  • Comprehensive health and dental coverage
  • Disability and life insurance
  • Office closure at the end of December
  • Additional supports to enhance your well-being throughout your career and beyond
  • Bilingualism Bonus of $800 per year
  • Relocation assistance
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