Technical Associate II, NAMs

MIT • Cambridge, MA

23h • Onsite

About The Position

The Technical Associate II, NAMs position in the Biological Engineering and Center for Gynepathology Research - Griffith lab will provide technical support for a newly awarded NIH Center grant focused on novel approach methodologies (NAMs) for Women’s Health. This role involves building and implementing living sex-specific liver patient avatars and endometriosis patient avatars for therapeutic development. The associate will also support the laboratory’s broader efforts to develop and apply advanced human liver microphysiological systems to improve prediction of disease biology and drug responses. Responsibilities include preparing and executing routine wet lab experiments under the supervision of a postdoctoral associate and in coordination with other laboratory members. The role will contribute to experimental activities such as assay execution, sample processing, cell culture workflows, and other laboratory tasks for the development and application of NAMs and microphysiological systems. The associate will perform mammalian cell culture and related experimental activities independently, including routine maintenance of cell lines and support for experiments involving primary cells or other specialized culture systems as needed.

Requirements

• Bachelor’s degree in biology, bioengineering, biomedical engineering, chemical engineering, or a related technical discipline.
• A minimum of four years of laboratory experience in biological research.
• Bench-top laboratory experience in biological research.
• Experience with cell culture, assay-based laboratory, aseptic technique, and mammalian cell culture.
• Experience with ELISA and other plate-based assays, flow cytometry, qPCR, western blot, or related molecular biology methods.
• Experience with immunostaining and/or microscopy, sample tracking, record keeping, and laboratory documentation.
• Experience with standard laboratory equipment such as microscopes, plate readers, and spectrophotometers.
• Detail-oriented, highly organized, and an excellent record keeper.
• Strong written and verbal communication skills.
• Ability to work both collaboratively and independently.
• Ability to manage multiple priorities.
• Ability to follow established protocols carefully.
• Ability to troubleshoot routine technical issues.
• Ability to maintain high standards of reproducibility and documentation.
• Proficiency with standard computer programs, including Excel, Word, and PowerPoint.

Nice To Haves

• Experience with translational research.
• Knowledge of liver biology, primary human hepatocytes, or liver-relevant cell systems.
• Experience with organ-on-chip systems, microfluidic platforms, 3D culture, tissue engineering, or related biomaterials-based methods.

Responsibilities

• Provide technical support for a newly awarded NIH Center grant focused on novel approach methodologies (NAMs) for Women’s Health.
• Build and implement living sex-specific liver patient avatars and endometriosis patient avatars for therapeutic development.
• Support the laboratory’s broader efforts to develop and apply advanced human liver microphysiological systems to improve prediction of disease biology and drug responses.
• Prepare and execute routine wet lab experiments under the supervision of a postdoctoral associate and in coordination with other laboratory members.
• Contribute to experimental activities, including assay execution, sample processing, cell culture workflows, and other laboratory tasks for development and application of NAMs and microphysiological systems.
• Perform mammalian cell culture and related experimental activities independently, including routine maintenance of cell lines and support for experiments involving primary cells or other specialized culture systems as needed.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level