Technical Associate I

MITCambridge, MA
Onsite

About The Position

The Technical Associate I in Mechanical Engineering, within the Traverso Lab, will provide crucial analytical and bioanalytical support for cutting-edge research in drug delivery systems, biomedical devices, biomaterials, and translational platforms. This role involves collaboration with leading institutions such as MIT, Brigham and Women’s Hospital, and the Broad Institute. The associate will be responsible for developing, optimizing, validating, and implementing analytical and bioanalytical methods for various research components including formulations, implants, ingestible devices, and biomaterials. A key part of the role involves processing diverse biological and formulation samples, such as plasma, serum, tissue, gastrointestinal fluids, and device extracts, using established preparation techniques. The position requires operating, maintaining, and troubleshooting a range of analytical instruments like HPLC, LC-MS, ICP-MS, GPC/SEC, DSC, DLS, UV-Vis, FTIR, and NMR. The associate will analyze complex datasets to aid in interpreting formulation performance, pharmacokinetics, biodistribution, device function, biocompatibility, and therapeutic efficacy. Additionally, responsibilities include managing sample intake, maintaining tracking systems, documenting methods and standard operating procedures, summarizing findings, and presenting results in lab meetings.

Requirements

  • Bachelor's degree in chemistry, analytical chemistry, chemical biology, biochemistry, chemical/biological/biomedical engineering, pharmaceutical sciences, or a field directly related to the work.
  • A minimum of two years of specialized laboratory experience, which may include experience gained as an undergraduate, co-op student, research assistant, or in an industry or academic research setting.
  • Hands-on experience with analytical chemistry and/or bioanalytical workflows, including sample preparation and quantitative analysis.
  • Experience with one or more analytical platforms such as HPLC, LC-MS, ICP-MS, GPC/SEC, DSC, DLS, NMR, UV-Vis, FTIR, or related instrumentation.
  • Experience processing biological, formulation, or device-associated samples for quantitative analysis.

Nice To Haves

  • Master’s degree.

Responsibilities

  • Develop, optimize, validate, and implement analytical and bioanalytical methods for formulations, implants, ingestible devices, biomaterials, and related technologies.
  • Process biological and formulation samples such as plasma, serum, tissue, gastrointestinal fluids, fecal samples, device extracts, and in vitro or ex vivo samples using established preparation techniques.
  • Operate, maintain, and troubleshoot analytical instrumentation including HPLC, LC-MS, ICP-MS, GPC/SEC, DSC, DLS, UV-Vis, FTIR, and NMR.
  • Analyze complex datasets to support interpretation of formulation performance, pharmacokinetics, biodistribution, device function, biocompatibility, and therapeutic efficacy.
  • Coordinate sample intake and maintain sample tracking systems.
  • Document analytical methods and standard operating procedures.
  • Summarize results and present findings at laboratory meetings.
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