Synthetic Medicinal Chemistry Intern
About The Position
Olema Oncology is dedicated to developing better medicines for breast cancer and beyond. Our lead program, palazestrant (OP-1250), is a complete estrogen receptor antagonist (CERAN) currently in development for metastatic breast cancer with blockbuster potential as a monotherapy and in combination in ER+/HER2- metastatic breast cancer. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with best-in-class potential. Our scientific breakthroughs are accelerated through the ways in which we fearlessly support, motivate, and challenge one another. At Olema, we know that when we put people first, our work becomes second to none. If you’re ready to join us at the edge of something unstoppable, let’s make a profound impact together for our patients, for your career, for what’s beyond. As the Synthetic Medicinal Chemistry Intern reporting to the Principal Research Associate, you will gain hands-on organic chemistry laboratory experience within a biotechnology environment working alongside our Medicinal Chemistry team. This role offers the opportunity to learn how to conduct organic chemistry experiments to synthesize compounds that will be evaluated in biological assays, contributing directly to ongoing research efforts.
Requirements
- Currently enrolled in a 4-year undergraduate program or 2026 graduate, required
- Currently a standing junior or senior, required
- Currently majoring in and/or taking Chemistry classes or closely related field of study, required
- Taken undergraduate-level Organic Chemistry; 2 semesters prior to the start of the internship, required
- Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment visa at this time.
Nice To Haves
- Previous hands-on laboratory experience in Organic Chemistry, strongly preferred
- Currently working in a research lab, strongly preferred
- Organized and detail-oriented
- Highly self-motivated with a strong desire to learn
- Strong interest in medicinal chemistry and drug discovery
Responsibilities
- Synthesizing, purifying, and characterizing small molecules in support of Olema drug discovery programs
- Conducting laboratory experiments in consultation with Chemistry team members
- Utilizing databases such as Reaxys or SciFinder to design and plan your experiments
- Acquiring and interpreting analytical data (eg. HPLC, LCMS, and NMR)
- Keeping excellent records of experimental procedures and acquired data in lab notebook
- Summarizing and presenting your experimental findings in group meetings
Benefits
- competitive compensation and benefits package
- open, flexible, and friendly work environment
- platform to develop their long-term careers
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What This Job Offers
Job Type
Full-time
Career Level
Intern
