Synthetic DNA Process Development Scientist
Eurofins USA Genomic Services•Louisville, KY
•Onsite
About The Position
Eurofins Scientific is an international life sciences company providing a unique range of analytical testing services. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production. The position requires an Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing.
Requirements
- Ph.D. or Master’s degree in Organic Chemistry or related field (required)
- Minimum 5 years of industrial experience in chemical synthesis
- Experience with solid-phase oligonucleotide synthesis
- Experience in oligonucleotide purification process development
- Strong analytical skills (HPLC, LC-MS)
- Experience scaling processes to manufacturing
Nice To Haves
- Experience in GMP or regulated environments
- Familiarity with automated DNA/RNA synthesizers
- Knowledge of modified nucleotides
- Experience in high-throughput oligo production
Responsibilities
- Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides
- Process development and scale-up from R&D to manufacturing
- Develop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting)
- Troubleshoot synthesis and purification challenges to improve yield and purity
- Collaborate with manufacturing, QC, and engineering for process transfer
- Evaluate new chemistries and technologies
- Author SOPs, batch records, and technical reports
- Ensure compliance with quality systems
- Mentor lab technicians
Benefits
- comprehensive medical coverage
- dental
- vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
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What This Job Offers
Job Type
Full-time
Career Level
Senior
