Supply Chain Manager, Materials Management and Planning

Obsidian Therapeutics•Bedford, MA

2d•$115,500 - $141,000•Hybrid

About The Position

Obsidian Therapeutics is seeking a highly motivated Supply Chain Manager with a strong background in supply planning, inventory management, and supplier relationship management within cGMP-regulated virtual manufacturing environments. This role is a key individual contributor within the Technical Operations team, responsible for leading material management activities to support clinical trials and the broader CMC roadmap. The position will drive the development of the company's first clinical stage autologous cell therapy program targeting solid tumors. The Supply Chain Manager will own the planning and availability of critical raw materials, oversee production planning, manage safety stock targets, and coordinate external storage and material transfers. This role will serve as the primary Supply Chain contact for internal teams and external partners on technical transfer and BLA readiness activities, including material specifications, BOM development, raw material risk assessments, and ensuring material readiness. The position is a hybrid role located in Bedford, MA.

Requirements

Bachelor’s Degree in Life Sciences, Supply Chain Management, or related discipline; advanced degree preferred.
6+ years of relevant experience in inventory management, planning, or supply chain in a biotech or pharmaceutical company, preferably in handling cell therapy or other similarly complex products.
Extensive quality and compliance background in a clinical GMP operational environment, including 3+ years prior experience in commercial or clinical GMP environment.
Ability to execute strategic objectives by focusing on critical near-term priorities while building toward long-term supply chain robustness for reliable delivery of complex treatments to patients.
Excellent analytical and problem-solving skills, with the ability to interpret complex data, make data-driven decisions, and clearly articulate business rationale and implications.
Excellent planning, coordination, and time management skills; You translate high level goals into plans, collaborate and adapt to meet objectives and timelines.
Excellent oral, written, and visual communication skills. You listen to understand and communicate effectively and persuasively with partners, colleagues, and leadership.
A desire and ability to work in a dynamic, collaborative environment; you build productive and healthy relationships within and across functions.
Collaborative and accountable – recognizes success requires teamwork and interdisciplinary thinking; you share feedback and constructively challenge and accept challenges to generate the best ideas to advance project and company goals.
Self-motivated, with a proven ability to meet objectives, timelines, and high standards managing multiple responsibilities in parallel.
Flexible – able to operate and adapt in a fast paced, rapidly developing environment.
Curious and humble – seeks and welcomes input/expertise of others, continuous learner.
Tenacious and resilient – is not easily overwhelmed by challenges, delivers on commitments, operates with urgency.

Nice To Haves

Strong knowledge of managing temperature controlled cold chains including 2-8C, -80C, and LN2 preferred: Prior experience in managing such shipments in collaboration with logistics partners.
Experience with Autologous Cell Therapy.

Responsibilities

Manage an End-to-End inventory management program through collaboration with external partners (Contract Manufacturing Organizations, External Biorepositories, Logistic Partners).
Manage a detailed End-to- End MRP process including the establishment of risk-based inventory targets.
Develop and manage a Sample inventory management program in partnership with Analytical Development and Quality Control groups.
Support the S&OP process through End-to-End supply planning and scenario analysis.
Support Raw Material risk assessment and Raw Material Qualification activities as part of BLA readiness activities.
Support the establishment of a supplier management program including the development of a sourcing strategy and the establishment of Supply Agreements.
Contribute to the development of a formal label management program.
Develop and maintain appropriate GMP controlled documents (i.e., SOPs, WIs, and Forms).
Manage the sourcing of Tumor Tissue to support development activities.
Coordinate various temperature controlled non-clinical shipments of raw materials between CDMOs and storage depots to support development and clinical processes.
Support multiple Raw Material and TIL CDMO relationships as the supply chain representative.