Staff Scientist

Benaroya Research Institute•Seattle, WA

12d•$72,950 - $111,610•Onsite

About The Position

The Long Lab within the Center for Translational Immunology at Benaroya Research Institute (BRI) is seeking a creative and highly motivated Postdoctoral Research Associate to investigate the immune mechanisms that drive type 1 diabetes (T1D) and other autoimmune diseases. The Lab combines advanced human immunology, single-cell and multi-modal technologies, and systems immunology approaches to better understand disease progression, patient variability, and response to therapy. Similar approaches are used in the Khor lab that studies Down’s Syndrome and immune aging, presenting a unique opportunity to gain exposure to projects that span immune mediated diseases. This collaborative position provides a unique opportunity to study immune regulation and autoreactive T cell during the earliest stages of T1D using cross-sectional, longitudinal and clinical trial samples. The successful candidate will lead independent cellular and molecular research and will work closely with BRI bioinformaticians and collaborators. This position is equivalent to an Instructor appointment in an academic setting and is ideal for scientists who have completed postdoctoral training and are interested in pursuing an advanced research career outside of the traditional faculty track.

Requirements

Ph.D. in Immunology or a related biomedical science.
Minimum of five years of postdoctoral research experience.
Experience in tissue culture and cellular and molecular biology techniques.
Demonstrated ability to independently design and execute complex research projects through to publication.
Strong publication record and evidence of scientific creativity, collaboration, and independent thinking.
Excellent written and verbal communication skills with experience presenting scientific findings.

Nice To Haves

Experience in human immunology, autoimmune disease, or type 1 diabetes research.
Experience with flow or spectral cytometry, single-cell technologies, systems immunology, and analysis of large-scale datasets.
Experience working with human clinical samples and translational research studies.
Familiarity with computational analysis tools and collaboration with bioinformatics teams.
Prior experience mentoring trainees and contributing to grant development.

Responsibilities

Design, lead, and implement multiple complex research projects focused on autoreactive B and T cell biology, immune tolerance, and autoimmune disease.
Design and perform experiments to identify autoreactive B and T cells for downstream transcriptional, single-cell, and multi-modal analyses.
Analyze, interpret, and document experimental data while maintaining rigorous scientific standards.
Use AI and collaborate closely with the BRI Bioinformatics team to integrate computational and systems immunology approaches into experimental design and data analysis.
Work collaboratively with investigators across BRI, the University of Washington, TrialNet, and other national and international collaborators.
Prepare manuscripts, abstracts, and presentations for publication and scientific meetings.
Contribute to the preparation of research grants, fellowship applications, and collaborative funding proposals.
Serve as a scientific leader within the Lab by mentoring research technicians, postdoctoral fellows, students, interns, and volunteers.
Help establish and optimize new Lab methods and workflows and oversee specialized instrumentation as appropriate.
Stay current with advances in immunology, autoimmune disease, and emerging technologies while identifying new scientific opportunities.
Foster a collaborative, inclusive learning environment that prioritizes integrity and respect, innovation and agility, and constant scientific inquiry.