Staff Engineer, Cell Culture Process Development

Takeda•Lexington, MA

21h

About The Position

The Staff Engineer, Process Development will advance BPD's platform development roadmap through technology-driven upstream process development. The role combines hands-on cell culture process development with data-driven approaches to improve process understanding, performance, and scalability. The successful candidate will apply expertise in cell culture, media development, cellular metabolism, and process analytics while collaborating with upstream program support teams and modeling experts to support biotherapeutic development. The position emphasizes integrating emerging technologies, advanced analytics, and systems-level thinking into next-generation cell culture platform development.

Requirements

PhD in Chemical Engineering, Biochemical Engineering, Bioengineering, Biotechnology, Biological Sciences, or a related discipline with relevant industrial experience; or a master's degree with 6+ years of relevant industry experience; or a bachelor's degree with 8+ years of relevant industry experience.
Experience in cell culture process development within a biopharmaceutical CMC environment.
Strong understanding of cell culture media development, cellular metabolism, and upstream bioprocessing fundamentals.
Demonstrated interest in data analytics, process modeling, and data-driven process optimization.
Experience designing, executing, and interpreting laboratory studies using bioreactor systems.
Excellent scientific communication, problem-solving, and collaboration skills.
Working knowledge of current Good Manufacturing Practices (cGMP).

Nice To Haves

Experience in metabolomics and systems-level process development.
Experience developing mechanistic, hybrid, or data-driven models for bioprocess development.
Familiarity with process automation, digital tools, data historians, and advanced analytics platforms.
Experience supporting clinical development programs and technology transfer activities.

Responsibilities

Independently design, execute, and interpret cell culture process development experiments.
Generate and communicate data-driven conclusions and technical recommendations.
Author study plans, technical reports, presentations, and development documentation.
Lead and contribute to cross-functional project teams and global initiatives.
Collaborate with program support teams and modeling experts to deliver project objectives.
Serve as a technical resource, mentor, and trainer for colleagues.
Evaluate and implement emerging technologies, analytical tools, and digital solutions.
Drive innovation and technical decision-making to improve process performance and platform capabilities.
Monitor industry trends and incorporate scientific advances into development strategies.
Foster a collaborative and knowledge-sharing culture across the organization.