Sr. Scientist I (Immunology) - in vitro & in vivo studies

ModeX Therapeutics • Weston, MA

6d

About The Position

ModeX Therapeutics is seeking a highly skilled and motivated Senior Scientist with immunology experience to support the development and progression of new immune therapies. The successful candidate will work with the ModeX team to test novel biologic drug candidates, define their mechanisms of action, and address biological questions. This role offers the opportunity to contribute to next-generation therapeutics as part of a cross-functional team in a fast-paced, rapidly growing biotech company.

Requirements

• B.S. or M.S. in immunology, immune-oncology, or a related field.
• 15+ years of relevant research experience, including 10+ years of industry experience.
• Strong hands-on expertise in immunology and immunotherapy, with the ability to independently evaluate and apply new concepts and immunoassays.
• Mastery of complex functional assays using primary immune cells, including multi-color flow cytometry, ELISA, and Luminex.
• Extensive in vivo study experience, including mouse handling, IV, IP, and SC dosing, tumor models, and tissue collection.
• Ability to work independently, prioritize effectively, and drive projects forward in a fast-paced biotech environment.
• Excellent written and oral communication, organizational, and data analysis skills.
• Strong troubleshooting and problem-solving skills.
• Collaborative mindset and confidence contributing new ideas and mentoring junior team members as needed.

Responsibilities

• Play a key role in developing new biologic drugs for immunotherapy.
• Independently propose, plan, and perform in vitro and in vivo studies to characterize drug candidates and their mechanisms of action.
• Establish mechanistic insights into the impact of novel targets on immune responses.
• Develop and perform complex functional assays using human, mouse, and NHP primary immune cells.
• Design, develop, troubleshoot, and establish in vitro assays, in vivo models, and standard operating procedures as needed.
• Collaborate with cross-functional project teams to support data-driven decision-making and timely program progression.
• Contribute to scientific communications, including internal reports and presentations.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior