Sr Scientist I, Discovery Biotherapeutics – Multispecifics Engineering
About The Position
Discovery Biotherapeutics at AbbVie is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting design, engineering, and production of multispecifics. This position will impact projects through engineering, production, and characterization of multispecific biopharmaceutical products. The ideal candidate should have experience with biologics and multispecifics production platforms, analytical characterization. It is preferred that the candidate would have experience with ADCs and/or Oncology focused multispecifics. The applicant should be an enthusiastic, creative scientist who will make tangible contributions to the continuous improvement and innovation within the organization.
Requirements
- PhD or MS degree in Biochemistry, Biochemical engineering or related disciplines
- Experience with protein, biologics, fragments, and multi-specifics design, expression and purification
- Strong molecular biology skills (e.g. molecular cloning) and experience with sequence analysis tools (Vector NTI, Geneious, Genedata)
- Experience with purification and automation instruments (e.g. Akta, Kingfisher, Hamilton)
- Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
- Excellent organizational skills and the ability to manage multiple projects simultaneously and adapt to rapid change in priorities
- Candidate must be a goal-oriented team player with excellent verbal and written communication skills, ability to operate in a fast-paced multi-disciplinary environment, and strong can-do attitude
Nice To Haves
- ADC and multispecific ADC design experience preferred
- Experience with developability screening for multispecifics preferred
- Experience with CRO coordination preferred
- Recognized in the scientific community through a sustained record of peer-reviewed publications and patents preferred
Responsibilities
- Responsible for design, engineering and production of multispecific biologics to support the Oncology therapeutic area.
- Evaluate and integrate state-of-the-art technology to improve therapeutic production platforms, and demonstrate creative “out-of-the-box” thinking to solve difficult problems
- Serve as a Multispecifics Engineering representative for cross-functional teams, and contribute scientific insights into multiple projects across various therapeutic areas; recognized expert in multispecifics design and production
- Identify and solve technical problems independently, conceive and implement innovative process research ideas
- Ensure consistency and quality of technical reports
- Provide project update, analysis and advice to cross-functional teams and senior management
- Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
Benefits
- paid time off (vacation, holidays, sick)
- medical/dental/vision insurance
- 401(k)
- short-term incentive programs
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
