Sr. Scientist, Delivery Sciences

Moderna • Cambridge, MA

1d • $130,800 - $209,400 • Onsite

About The Position

We are seeking an accomplished Scientist to lead the development of targeted lipid nanoparticle (LNP) formulations within our fast-paced, cross-functional R&D organization. In this role, you will advance the science of LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver and leverage state-of-the-art analytical techniques to establish structure–function relationships that drive biological performance. You will also integrate high-throughput formulation, laboratory automation, and AI/ML-enabled approaches to accelerate LNP discovery and support data-driven decision-making across multidisciplinary research programs.

Requirements

• Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
• Deep expertise in lipid nanoparticle (LNP) design, formulation, and physicochemical characterization, with experience advancing targeted or extra-hepatic delivery platforms preferred.
• Demonstrated experience implementing high-throughput formulation workflows, laboratory automation, and computational or AI/ML-enabled data analysis to accelerate discovery and support data-driven decision-making.
• Proven leadership experience mentoring scientists and research associates, with a track record of driving cross-functional collaboration and delivering research objectives in a fast-paced environment.
• Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment

Nice To Haves

• Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting
• Clear, concise scientific communication—written and verbal—with a track record of peer-reviewed publications and/or patents
• Commitment to inclusive teamwork, continuous learning, and high scientific rigor

Responsibilities

• Drive research programs on targeted, extra-hepatic LNP delivery—from hypothesis generation through in-vitro / in-vivo evaluation
• Develop and optimize LNP self-assembly processes; refine composition, payload loading, and surface modifications for tissue and cell-type specificity
• Advance LNP formulation discovery by leveraging high-throughput formulation, automation, and AI/ML-enabled data analysis to accelerate innovation, optimize formulations, and drive data-informed decision-making across multidisciplinary teams
• Independently Design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership
• Implement and innovate advanced physicochemical and biophysical characterization methods (e.g., DLS, CryoEM, SAXS, ITC, NMR, nFCM etc) to elucidate structure–function relationships
• Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations
• Provide scientific leadership and mentorship to research associates while partnering with cross-functional teams and external collaborators to prioritize activities, solve technical challenges, and ensure the timely achievement of project objectives and key milestones.

Benefits

• Competitive healthcare, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help you plan for the future
• Location-specific perks and extras

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree