Sr. Scientist, Biology-Discovery

MerckUpper Gwynedd Township, PA
$117,000 - $184,200Onsite

About The Position

We are seeking a highly motivated and experienced Senior Scientist to join our Infectious Diseases and Vaccines discovery team. This laboratory-facing role focuses on advancing our therapeutic pipeline for chronic viral diseases. The successful candidate will leverage deep technical expertise in virology to lead assay development and platform innovation. The primary focus of this role is discovery and translational research targeting hepatitis B virus (HBV) and related DNA viruses. We value creative thinking, goal-oriented teamwork and the application of generative AI models to define and enable problem-solving.

Requirements

  • PhD in Virology, Immunology, or a closely related biomedical science discipline (preferred).
  • Minimum of 2–5 years of postdoctoral research or pharmaceutical/biotech industry experience preferred.
  • Extensive, documented research experience working directly with hepatitis B virus (HBV) or related pathogenic DNA viruses.
  • MS degree in Biology or Biomedical Sciences with a minimum of 7 years of experience in industry and or academia working with DNA viruses, experience with HBV preferred.
  • BA/BS degree in Biology or Biomedical Sciences with a minimum of 10 years of experience in industry and or academia working with DNA viruses, experience with HBV preferred.
  • Deep understanding of chronic viral disease pathogenesis and host-pathogen interactions.
  • Proficiency in core virology techniques, including viral culture, quantification, and neutralization assays.
  • Expert command of molecular biology methods (e.g., qPCR, digital PCR, cloning, next-generation sequencing).
  • Strong communication skills with a demonstrated ability to collaborate in a fast-paced matrix environment.
  • Assay Development
  • Biochemical Assays
  • Cell Culture Techniques
  • Detail-Oriented
  • Drug Target Identification
  • Hepatitis B
  • Immunology
  • Molecular Biology
  • Molecular Microbiology
  • Personal Initiative
  • Project Leadership
  • Viral Culture
  • Viral Replication
  • Virology

Responsibilities

  • Conduct hands-on bench research utilizing advanced virology and molecular biology techniques.
  • Design, optimize, and validate robust in vitro and ex vivo viral replication and infection assays.
  • Develop innovative technological platforms to evaluate novel therapeutic candidates and mechanisms of action.
  • Serve as the scientific lead on cross-functional project teams, driving experimental strategies and timelines.
  • Analyze complex datasets, interpret results, and present actionable findings to senior leadership.

Benefits

  • medical, dental, vision healthcare and other insurance benefits (for employee and family)
  • retirement benefits, including 401(k)
  • paid holidays, vacation, and compassionate and sick days

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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