Sr. Research Associate, Drug Product Development

Crinetics Pharmaceuticals•Headquarters, KY

2d•$82,000 - $103,000•Onsite

About The Position

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others. The Senior Research Associate, Drug Product Development, will support the development of drug product formulations from early preclinical enabling studies through clinical supply for First-in-Human (FIH) trials. This role will contribute hands-on laboratory execution, data analysis, and technical documentation in support of formulation development for oral and/or parenteral dosage forms. The position works closely with formulation scientists, analytical, DMPK, toxicology, and manufacturing teams to deliver high quality drug products in a fast-paced development environment.

Requirements

Bachelor’s or Master’s degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related field.
Minimum of 3–5 years of experience in pharmaceutical formulation development, with demonstrated hands-on lab experience.
Experience supporting preclinical and/or clinical formulation development, ideally through FIH.
Experience with oral dosage forms and/or parenteral formulations. Familiarity with common formulation techniques and excipients.
Strong organizational skills and attention to detail.
Strong laboratory execution and problem-solving skills.
Ability to work under minimal supervision while contributing effectively in a team environment.
Knowledge of regulatory expectations related to early-phase CMC development; exposure to GMP manufacturing and/or clinical supply preparation is a plus.
Excellent interpersonal skills, with strong oral/written communication and presentation skills.
Ability to author and review relevant development reports.
Ability to work in cross functional teams as related to drug development with a collaborative mindset with a proactive, solution-oriented approach.
Ability to manage multiple priorities in a dynamic environment.

Responsibilities

Perform hands-on formulation development activities for preclinical and early clinical drug products, including FIH studies.
Prepare and evaluate formulations for in vivo (PK, tox) and clinical use.
Execute laboratory experiments including formulation preparation, characterization, and stability testing.
Maintain accurate and well-documented experimental records in electronic laboratory notebooks (ELNs).
Support scale-up, tech transfer, and manufacturing activities for clinical supplies.
Assist in preparation of protocols, reports, and CMC documentation to support regulatory submissions.
Collaborate cross-functionally with analytical, DMPK, toxicology, quality, and external partners/CDMOs.
Troubleshoot formulation and manufacturing challenges; propose practical solutions.
Ensure compliance with internal procedures and applicable GMP/GxP requirements as needed.