Sr. Research Associate, Clinical Biomarker Laboratory, Flow Cytometry
About The Position
Moderna is seeking a talented and motivated Senior Research Associate to join the Clinical Flow Cytometry group to serve as a technical expert for the generation of high parameter flow cytometry data under GCLP guidelines to support clinical programs across multiple therapeutic areas. The Senior Research Associate will work with a team of scientists to return high quality data for clinical trials conducted by Moderna. This will include development of cell-based flow cytometry assays, performing fit-for-purpose validations, and executing clinical sample testing. You will be an integral part in applying high parameter flow and complex assays to generate key clinical data to drive clinical trial decisions.
Requirements
- BS or MS in Immunology, Life Sciences, Biology, or related field; 3+ years lab experience
- Direct flow cytometry experience from sample processing and staining, through sample acquisition
- Experience with cell culture, ex vivo assays, and cell isolation from tissues
- Possess good computational skills, experienced with Word, Excel, Power Point, and GraphPad Prism
- Demonstrated level of independence
- An effective communicator and collaborator in a project team with good written and presentation skills
- Flexibility with changing priorities and urgent project requests
Nice To Haves
- Experience in a regulated lab is desired
- Experience in assessing cell-mediated immunity through flow cytometry: ex vivo stimulation of PBMC and intracellular cytokine staining for functional profiling is desired
Responsibilities
- Execute clinical sample testing under GCLP guidelines
- Conduct ex vivo stimulation for functional profiling of immune responses using intracellular cytokine staining on clinical trial PBMC samples
- High parameter immunophenotyping on PBMCs, whole blood samples, and tissue samples
- PBMC isolation and cryopreservation from blood products
- Strict adherence to protocols related to technical details and documentation to ensure assay rigor and repeatability
- Deliver high quality data within defined timelines and aligned to current industry expectations
- Play a prominent role in a team developing high parameter spectral flow cytometry assays and applying them to clinical trial samples to generate key data.
- Adhere to established experimental workflows and documentation procedures while working to improve processes for accuracy and efficiency
- Run experiments independently from sample prep to acquisition, and accurately analyze (FCSExpress) and present data
- Under the direction of the Study Lead, participate in assay development and validation studies
- Work with the team to identify, test feasibility, and implement emerging laboratory techniques
- Assist in general lab organization and other shared duties
- Maintain and support safe lab practices and environment
Benefits
- Competitive healthcare, plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
- Family planning benefits, including fertility, adoption, and surrogacy support
- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
- Savings and investments to help you plan for the future
- Location-specific perks and extras
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Associate degree
