Sr. Purification Chemist

Corden Pharma Colorado• Boulder, CO, US, CO

1d•$100,500 - $125,500•Onsite

About The Position

The Sr. Purification Chemist contributes to providing strong technical leadership and documentation support for development and GMP manufacturing processes. This role is responsible for the planning and execution of multi-step preparative chromatography from laboratory to full commercialization. The emphasis is on the creative application of a full range of literature and theoretical concepts, from a diverse range of chemistry to the design and implementation of cost-effective processes for the manufacture of Corden Pharmaceuticals. The role involves working within a team-oriented environment with professionals from a variety of disciplines. The Sr. Purification Chemist conducts research, analysis, synthesis, experimentation, and documentation for purposes such as process development, implementation, registration, validation, and process improvement.

Requirements

Bachelor’s Degree (BS) in Organic or Analytical Chemistry and 2 years related experience and/or training in purification chemistry; or equivalent combination of education and experience.
Ability to read, analyze, and interpret common scientific and analytical journals, financial reports, and legal documents.
Ability to respond to common inquiries or complaints from customers, regulatory agencies, or members of the business community.
Ability to write speeches and articles for publication that conform to prescribed style and format.
Ability to calculate figures and amounts such as proportions, percentages, area, circumference, and volume.
Ability to apply concepts of basic algebra and geometry.
Ability to convert units of measurement.
Ability to apply principles of logical or scientific thinking to a wide range of intellectual and practical problems.
Ability to deal with nonverbal symbolism (formulas, scientific equations, graphs, etc.) in its most difficult phases.
Ability to deal with a variety of abstract and concrete variables.
Ability to apply scientific methods to experimentally prove cause and effect.
Strong background in Purification Chemistry or a related scientific field.
Working knowledge of regulatory issues in Pharmaceutical Manufacturing including cGMPs, PSM, OSHA, and EPA requirements.
Communicates effectively in writing and verbally within the department.
Computer skills in the areas of Microsoft Office Products – Word, Excel, PowerPoint.
Ability to work interactively within a multi-functional team-oriented environment.
Takes initiative in setting own goals and work plan.
Hands on purification laboratory experience.
Broad technical knowledge in Purification Chemistry and Process Improvement Methodology.
Maintain a well-documented record of work performed in a laboratory notebook, laboratory reports, and campaign reports.
Experience in the purification of Peptides.
A working knowledge of all plant-scale purification unit operations, scale-up, and plant design considerations.
An understanding of chemical reactivity, potential exotherms, cross reactivity, side products, and waste streams, especially for processes they support.
Regularly seeks out new learning opportunities beyond basic skills that can result in innovative approaches to technical issues.
Demonstrates clear understanding of technical issues and the requirements of a viable manufacturing process; has demonstrated independent support on multiple (not necessarily simultaneous) processes.
Identifies areas where change/continuous improvement is beneficial to the business, and successfully defends and implements projects.
Assumes reasonable risk in trying out new, self-generated ideas.
Proactive approach to problem identification and resolution.
Communicates effectively in writing and verbally within and across departments and to site management; updates are clear, selective and effective.
Ability to understand and apply statistical design of experiments and draw sound conclusions from the results; uses results when solving problems or proposing improvements.
Ability to provide leadership in all Purification Chemistry aspects of manufacturing processes; leads teams in the development, transfer, troubleshooting, and improvement of chemical processes in an interactive, interdisciplinary team environment.
Seeks out opportunities to learn manufacturing needs and methods that facilitate substantial process improvements; acquires new skills in state-of-the-art technology and applies it to their assignments.
Demonstrates skills in negotiation and influencing others.

Responsibilities

Develops and supports scalable purification processes and analytical methods while providing technical expertise and support during lab or plant operations.
Independently plans and executes experiments for the purification of peptides, toward developing a robust commercial process, while working on a project team.
Works effectively in a team-oriented environment.
Presents work orally and in form of written development reports.
Adheres to cGMP and SOPs in all aspects of work.
Demonstrates a clear understanding of technical issues and the requirements of a viable manufacturing process.
Ensures that the purification is capable of meeting cost, yield, throughput, quality, and QSHE goals on assigned processes.