Sr. Product Manager, Clinical Studies & SampleMinded Research

Exact Sciences • Madison, WI

4d • Onsite

About The Position

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others. Position Overview The Sr. Product Manager, Clinical Studies & SampleMinded Research (SMR) owns the SMR product and vision while partnering with clinical study teams and our Precision Oncology and Screening business units. This role ensures that SMR evolves to meet study needs by aligning product strategy, roadmap, and delivery with clinical, lab, and operational requirements. The Sr. Product Manager drives end-to-end delivery, translates study needs into prioritized product features, and supports study intake where SMR is involved. They serve as the primary point of contact for SMR-related questions and ensure alignment between study expectations and product capabilities by identifying risks, gaps, and dependencies. In addition, the Sr. Product Manager collaborates closely with Clinical Affairs, CASO, lab teams, and IT partners to align on workflows, integrations, and system dependencies related to SMR. The role requires strong cross-functional leadership and the ability to navigate complex, matrixed environments, ensuring clear communication and coordination across stakeholders while maintaining focus on delivering high-quality product solutions. This position leads requirement definition, including user stories and acceptance criteria, and ensures that delivered solutions meet both stakeholder needs and product standards. The Sr. Product Manager balances strategic thinking with execution, continuously analyzing opportunities to improve SMR capabilities and support a growing portfolio of clinical studies. While this role engages with clinical programs, accountability remains focused on SMR product outcomes, with broader study execution and IT coordination responsibilities residing within program and clinical teams. The ideal candidate brings strong product management experience, a demonstrated ability to work across clinical and technical domains, and a passion for solving complex problems in support of advancing cancer diagnostics.

Requirements

• Bachelor’s Degree in a field related to essential duties; or Associates Degree and 2 years of relevant experience; or High School Diploma or General Education Degree (GED) and 4 years of relevant experience.
• 5 years of relevant professional experience as outlined in the essential duties.
• Experience leading cross-functional teams to deliver products/services.
• Experience applying techniques and methods of modern product management, product discovery, and product delivery – along with expertise with product management platforms and tools.
• Demonstrated ability to facilitate the development of product vision, strategic roadmaps, and go-to-market strategy for services and products as part of a broader end-to-end user experience.
• Advanced problem-solving, organizational, and analytical skills with the ability to evolve product strategy based on research, data, and industry trends.
• Advanced business analysis skills including, but not limited to, process and user flow definition and business KPIs.
• Advanced skills in translating complex user, business, operational, and technical requirements into clear epics, features, stories, and acceptance criteria.
• Some experience with A/B testing, user testing, user interviews, and conversions funnels.
• Experience engaging with engineers, designers, researchers, SMEs, and company leaders in a constructive and collaborative relationship where you can both learn and influence.
• Demonstrated ability to perform the essential duties of the position with or without accommodation.
• Applicants must be currently authorized to work in country where work will be performed on a full or part-time basis.
• We are unable to sponsor or take over sponsorship of employment visas at this time.

Nice To Haves

• Bachelor’s Degree in Life Sciences, Engineering, Operations, Business, or related field.
• Experience in life sciences, healthcare, diagnostics, or other regulated environments, with strong technical and systems understanding (e.g., integrations, APIs, enterprise platforms)
• Experience working in Agile/Scrum frameworks, with familiarity in using data and analytics tools to inform product decisions.

Responsibilities

• Demonstrate complete knowledge, skills, and understanding of practices for complex programs and initiatives exhibiting creativity and substantial understanding of specialized techniques, processes, and procedures.
• Engage as a key voice of the customer for stakeholders for one or more product areas to ensure their needs are heard and that delivery teams are getting the support needed.
• Translate user and business needs into high-level requirements for work assignments of medium complexity, by utilizing a structured process for gathering, analyzing, documenting, and managing change to assess and recommend solutions based on cost vs. benefit analysis and parallels to overall business strategy.
• Define acceptance criteria for product features of medium complexity and ensure they are understood by the delivery team.
• Maintain detailed documentation such as gap analyses, business process flow charts, decision tables, features, and business requirements document to aid in the development and refinement of new analytical tools and processes.
• Execute plans during the implementation phase, composing standard operating procedures (SOPs), participating in design reviews and walk throughs.
• Track product performance after implementation to ensure efficiency of operations and proactively provide continuous improvement recommendations.
• Define key performance indicators (KPIs) and metrics to measure product success.
• Monitor product performance, analyze data, and make data-driven decisions to improve product outcomes.
• Collaborate closely with Quality Engineering (QE) to ensure the product meets high standards of quality, performance and reliability by defining the product requirements and acceptance criteria, which are then used by the QE team to develop test plans and test cases.
• Create and maintain the product roadmap for area of responsibility that outlines the development and release of features.
• Communicate product strategy, roadmap, and progress to stakeholders, including executives, partners, and customers.
• Manage stakeholder expectations and prioritize competing demands to ensure alignment and focus.
• Actively participate in all squad ceremonies.
• Review work completed by the squad, provide feedback, and accept work, as applicable.
• Manage the product backlog by grooming and prioritizing, while ensuring work is in line with product strategy and OKRs.
• Develop and maintain relationships with customers and business partners to drive satisfaction.
• Consistently influence and make significant decisions within a project, demonstrating good judgment in selecting methods and techniques for obtaining solutions based in a solid understanding of business strategy and best practices with minimal instructions for difficult or unpredictable situations.
• Ability to collaborate and operate in a cross-cultural and complex matrixed environment to build consensus across functions.
• Contribute individual capabilities to the achievement of group objectives and work effectively with others in a group setting. This includes mentoring, coaching, and technical guidance for junior members of the team.
• Communicate clear and concise product updates and releases to internal and external stakeholders.
• Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
• Support and comply with the company’s Quality Management System policies and procedures.
• Maintain regular and reliable attendance.
• Ability to act with an inclusion mindset and model these behaviors for the organization.

Benefits

• paid time off (including days for vacation, holidays, volunteering, and personal time)
• paid leave for parents and caregivers
• a retirement savings plan
• wellness support
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: High school or GED