Sr Principal Eng - Process Engineering

Johnson & Johnson • Gurabo, PR

8d • Hybrid

About The Position

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way! Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for a Sr Principal Eng - Process Engineering to join our Team! This is an onsite/hybrid role. Please note that this role is available across multiple countries and may be posted under different requisition numbers to align with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s): Belgium & Italy- Requisition Number: R-071736 Puerto Rico - Requisition Number: R-076777 Switzerland - Requisition Number: R-076783 Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission. Position Summary As the GET PE – Synthetics Drug Product Manufacturing Senior Principal Engineer , you will lead early design inputs and technical strategy for synthetic’s drug product manufacturing processes within strategic capital projects, network studies, and technology platforms across IMSC. You will provide deep technical expertise in the synthetic’s controlled bioburden-drug product manufacturing (OSD and innovative forms such as semi-solid) and drug product intermediate through bioavailability enhanced technologies , while supporting solving and optimization activities at internal and external manufacturing sites. Joining our global engineering group, you will collaborate with high‑performing, multi-functional teams across multiple sites and functions. This role offers a dynamic and inspiring work environment with significant opportunities to influence technology direction, standardization, and capability building across the network.

Requirements

• Minimum of a Master’s degree or equivalent experience in Engineering, Pharmaceutical Sciences, or a related technical field is required
• Minimum 10 years of relevant experience in synthetics controlled bioburden drug product manufacturing , with a strong focus on oral solid dose (OSD) processes and innovative technologies (e.g semi-solid) in drug product pharmaceutical manufacturing environments
• Demonstrated expertise in bioavailability enhanced technologies , including ASD (amorphous solid dispersions) —with deep knowledge of spray drying —and SEDDS or similar innovative enabling formulation approaches
• Proven experience with OSD controlled bioburden manufacturing , including batch and continuous manufacturing processes and associated equipment
• Strong understanding of cGMP environments and regulatory expectations for controlled bioburden-drug product manufacturing.
• Aseptic capability is a plus
• Proven track record of leading multi-functional teams and influencing technical decisions in complex, global organizations
• Ability to support early‑phase design, detail design, Start‑up processes and Commissioning & Qualification (C&Q) of controlled bioburden (and aseptic) equipment
• Experience with inherently safe containment design for components with low exposure level
• Drive the adoption of digital and data‑enabled solutions for DP manufacturing, including real‑time monitoring, advanced process control, advanced analytics, model and simulation, and smart manufacturing use cases where they improve reliability and performance
• Strong customer management and communication skills, with the ability to influence across sites, functions, and external partners
• Strategic attitude combined with hands‑on technical capability
• Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture
• Proficiency in written and spoken English
• Willingness to travel up to 25% domestically and internationally

Nice To Haves

• Strategic attitude combined with hands‑on technical capability
• Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture
• Additional languages (Dutch, Spanish, Italian) are an advantage

Responsibilities

• Lead the intake, scoping, prioritization, and resolution of synthetics controlled bioburden - drug product manufacturing related technical requests across global sites
• Lead and influence early‑phase process design and domain expertise for oral solid dose (OSD) products, covering both batch and continuous manufacturing platforms ; as well new innovative drug product forms
• Lead and influence early‑phase process design and domain expertise for bioavailability enhanced technologies , including amorphous solid dispersions (ASD) with a strong emphasis on spray drying , as well as other technologies such as Self-Emulsifying Drug Delivery Systems (SEDDS) and other related innovative drug product intermediate formulation approaches
• Ensure robust, fit‑for‑purpose process design while promoting standardization and platform approaches where they make valuable contributions
• Provide expert input and alignment on key process, equipment, and technology selection decisions for drug product manufacturing
• Actively collaborate with other functions such as R&D, MSAT, Quality, EHS and Operations leads across synthetic drug product sites
• Find opportunities for harmonization, shared solutions, and best‑practice exchange across the network
• Foster a culture of collaboration to reduce duplication, accelerate implementation, and improve speed‑to‑market
• Maintain strong connections with industry experts and external networks (e.g., ISPE) to bring innovative drug product manufacturing solutions into the organization
• Ensure alignment with enterprise strategies, GMP requirements, and technology roadmaps
• Collaborate with External Manufacturing teams to prioritize support and resolve issues for high‑impact programs and partners

Benefits

• Vacation –120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
• Holiday pay, including Floating Holidays –13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year

What This Job Offers

• Job Type: Full-time
• Career Level: Principal