Sr. Manager, Clinical Operations

10x Genomics•Pleasanton, CA

3d•Onsite

About The Position

The Sr. Manager, Clinical Operations reporting to the Director, Business Development and Strategic Partnerships will drive the operational execution and strategic management of high-impact alliances central to 10x Genomics’ effort to advance future diagnostic applications for single cell and spatial technologies. Key responsibilities for this role include: managing a portfolio of academic collaborations and strategic partnerships according to established milestones and outcomes, leading the operational execution for large-scale, multi-year collaborations with premier academic institutions to generate evidence for future clinical applications of single-cell and spatial technologies, and driving collaboration between internal cross-functional teams and external partners to achieve desired results. The ideal candidate is an action-oriented and highly-effective leader who has previously managed clinical research studies involving large numbers of patient samples and complex molecular testing or biomarkers.

Requirements

An Advanced degree (M.S., PharmD, Ph.D., M.B.A.) in a Life Science, Clinical, or related field is required.
8+ years of relevant industry experience with 4-5 years of experience in Clinical Operations within the diagnostics, biotechnology, or pharmaceutical industry.
Direct experience managing research studies involving large numbers of patient samples and complex molecular testing or biomarkers
Deep understanding of clinical study execution, site management, and the complexities of clinical sample logistics and chain of custody.
Demonstrated ability to manage competing priorities, swiftly resolve complex operational problems, and drive tangible results.

Nice To Haves

Preferably, experience in managing high-value strategic alliances and driving value through the successful execution of collaborative research, development, or commercialization agreements.
Thrives in a fast-paced environment with a ‘roll up your sleeves and get it done’ mentality.
Excellent at communicating, organizing, and leading external stakeholders and internal cross-functional teams to achieve desired outcomes.
Comfortable leading through ambiguity and change; focusing on finding practical solutions and driving clarity to maintain program momentum.
Exceptional at building strong, collaborative relationships with diverse stakeholders, including external investigators, and internal technical and executive teams.
Willing to travel up to 25% for site visits, investigator meetings, and external partner engagement.
Startup or small biotech experience.
Familiarity with CLIA/CAP standards as they relate to samples sent to a centralized testing laboratory is preferred.

Responsibilities

Manage the operational execution of large-scale, longitudinal clinical research studies according to established agreements with academic institutions
Own and drive clinical research study timelines, deliverables, and operational plans ensuring adherence to sampling schedules; identify operational risks regarding enrollment, setup, or logistics early, implementing mitigation strategies to maintain study integrity.
Establish and enforce auditable procedures for sample collection, tracking, and chain of custody, ensuring compliant transport from clinical sites to 10x Genomics laboratory.
Manage the study budgets, including the oversight of reimbursement, equipment provisioning, and consumables provided to partner sites.
Ensure all study activities comply with IRB protocols, patient consent requirements, and GCLP/CLIA standards where applicable.
Manage a diverse, high-value portfolio of academic collaborations and strategic partnerships to ensure all projects and agreements track toward established milestones and outcomes.
Act as the primary liaison between internal teams and key stakeholders at relevant academic institutions and industry partners to foster strong, collaborative relationships that drive engagement and performance.
Oversee compliance with contractual obligations, milestones, and deliverables, working closely with Legal, Finance, and Business Development to drive contract amendments or renewals as needed.