Sr. Manager, Bioinformatics

Illumina • San Diego, CA

1d • $170,600 - $255,800 • Remote

About The Position

The Sr. Manager, Bioinformatics will lead a team of bioinformatics scientists supporting Illumina's Clinical Genomics portfolio, including oncology, reproductive health, and regulated clinical sequencing products. The role oversees bioinformatics activities supporting assay development, software releases, regulatory submissions, and product commercialization. It partners with cross-functional teams to deliver high-quality bioinformatics solutions that support product development and customer success.

The role also manages portfolio prioritization, resource allocation, and risk across multiple programs; oversees development, validation, and deployment of analytical methods and workflows; and supports product adoption and lifecycle management. The manager works with customers, commercial teams, and external collaborators to resolve technical challenges and gather feedback, while advancing analytical approaches and scalable solutions.

Requirements

• Bachelor’s degree and a minimum of 12 years of related experience, typically required.
• 3–6 years of management experience.
• Demonstrated experience leading bioinformatics teams and complex cross-functional programs.
• Experience supporting regulated products, including IVD, CDx, FDA, IVDR, or similar regulatory frameworks.
• Strong understanding of next-generation sequencing, genomics data analysis, and bioinformatics pipeline development.
• Experience supporting customers, commercial teams, or external collaborators in deploying and adopting genomics products and bioinformatics solutions.
• Proficiency with bioinformatics software development and analysis tools, including Python, R, and Linux-based environments.
• Excellent communication, stakeholder management, and organizational leadership skills.

Nice To Haves

• PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or a related scientific discipline, with 8+ years of relevant experience.

Responsibilities

• Lead, mentor, and develop a team of bioinformatics scientists, fostering collaboration, innovation, and technical excellence.
• Manage bioinformatics activities for Clinical Genomics product development, commercialization, and lifecycle management, including portfolio prioritization, resource allocation, and risk management across programs.
• Oversee development, validation, and deployment of analytical methods and bioinformatics workflows for customer-facing software, assays, and regulated products.
• Collaborate with R&D, Software Engineering, Biostatistics, Regulatory, Quality, Product Management, and Commercial teams to achieve program objectives and business goals.
• Partner with customers, commercial teams, and external collaborators to support product adoption, provide bioinformatics expertise, troubleshoot technical challenges, and gather feedback.
• Drive evaluation and adoption of analytical approaches, technologies, and scalable bioinformatics solutions that advance product capabilities, operational efficiency, and customer value.

Benefits

• Variable cash program (bonus or commission).
• Equity may be included for eligible roles.
• Access to genomics sequencing.
• Family planning benefits.
• Health, dental, and vision benefits.
• Retirement benefits.
• Paid time off.
• Employee Resource Groups offering career development experiences, cultural awareness, and social responsibility opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior