Sr Infrastructure Engineer

Baylor Genetics • Houston, TX

6h • Hybrid

About The Position

The Senior Infrastructure Engineer serves as the designated backup and knowledge-continuity resource for Baylor Genetics’ on-premises data center and network environment. This role exists to ensure uninterrupted operation of the critical infrastructure supporting our genomics pipeline and clinical laboratory systems, and to eliminate single points of failure in IT operations. This role may evolve as organizational needs change. The role exists to sustain, document, and be fully capable of independently operating all core on-premises infrastructure — servers, storage, networking, and security systems — in any operational scenario, including emergency coverage of the primary infrastructure lead. This role impacts clinical laboratory operations, genomics pipeline throughput, and the reliability of all on-premises and hybrid-connected systems used across the organization. Success looks like: zero unplanned outages attributable to single-person dependency, a fully documented environment with up-to-date runbooks, and the demonstrated ability to assume full infrastructure ownership without disruption.

Requirements

• Bachelor’s degree in Information Technology, Computer Science, or a related field; or equivalent technical training and experience.
• 7+ years of hands-on enterprise IT infrastructure engineering experience in a complex, predominantly on-premises environment.
• Deep expertise in physical and virtual server administration (Windows Server 2016/2019/2022, Linux) including VMware vSphere or Microsoft Hyper-V.
• Strong networking fundamentals: routing, switching, VLANs, firewall policy management, and systematic network troubleshooting (Cisco, Palo Alto, Fortinet, or equivalent).
• Experience managing physical data center environments — rack/stack, structured cabling, power, and cooling awareness.
• Proficiency with SAN/NAS storage platforms and enterprise backup/recovery systems (Veeam, Commvault, or equivalent).
• Working knowledge of Microsoft 365 and Azure Active Directory in a hybrid on-premises/cloud context.
• Strong documentation discipline: ability to produce clear runbooks, network diagrams, and standard operating procedures independently.
• Proven ability to rapidly learn complex, undocumented environments and operate independently under high-pressure conditions.
• Equivalent combination of education and experience may be considered.

Nice To Haves

• Experience in a healthcare, clinical laboratory, genomics, or other regulated life sciences environment.
• 7+ years of progressive experience in enterprise infrastructure roles with demonstrated ownership of critical systems.
• Relevant certifications: CCNA/CCNP, VCP-DCV, MCSE, CompTIA Network+/Security+, or equivalent.
• Familiarity with HPC or high-throughput bioinformatics pipeline infrastructure.
• Exposure to HIPAA compliance requirements, NIST frameworks, or SOC 2 audit environments.
• Scripting proficiency (PowerShell, Bash, or Python) for infrastructure automation and administrative efficiency.
• Experience with monitoring platforms such as PRTG, SolarWinds, Zabbix, or similar tools.

Responsibilities

• Serve as the designated backup for the primary infrastructure lead — assume full operational control of data center, network, and server environments during absences, emergencies, or transitions to ensure zero service interruption.
• Administer and maintain physical and virtual server infrastructure (Windows Server, Linux, VMware/Hyper-V), including provisioning, patching, performance monitoring, and capacity planning to sustain 99.9%+ uptime.
• Manage LAN/WAN networking operations including switches, routers, firewalls, and VLANs to maintain high availability and security across all on-premises systems.
• Build, maintain, and continuously improve runbooks, network diagrams, and disaster recovery documentation to eliminate single points of failure and reduce mean time to recovery.
• Support and sustain the on-premises genomics pipeline infrastructure, ensuring compute and storage resources meet demanding throughput and availability requirements for clinical laboratory operations.
• Collaborate cross-functionally with bioinformatics, clinical lab, and IT teams to align infrastructure reliability with patient-impacting laboratory workflows.
• Proactively identify and remediate risks including aging hardware, technical debt, and configuration vulnerabilities — presenting actionable proposals to leadership.
• Respond to infrastructure incidents and outages with urgency, including after-hours escalations, to minimize downtime impact on laboratory and clinical operations.
• Perform other duties as assigned to support team and organizational objectives.
• Comply with all company policies, procedures, and applicable regulatory requirements.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior