Sr. Director, Epidemiology & RWE Analytics

Neurocrine Biosciences • San Diego, CA

1d • $230,100 - $314,000

About The Position

Provides senior leadership for enterprise-wide epidemiology and real-world evidence (RWE) strategy, governance, and execution across therapeutic areas and portfolios. Accountable for defining and delivering fit-for-purpose, consistent evidence strategies that support clinical development, regulatory submissions, medical affairs, and market access. Serves as a senior thought partner to R&D, Medical, Market Access, and Analytics leadership and leads teams responsible for high impact, externally facing epidemiologic and RWE programs.

Requirements

• Master's Degree AND 12+ years of relevant experience OR PhD, PharmD, or MD in Epidemiology, Public Health, or a related field AND 10+ years of pharmaceutical or biotech experience in epidemiology and/or real-world evidence.
• Previous management experience
• Acts as a "trusted advisor" across the company and may be recognized as an external expert
• Provides strategy, vision and direction regarding issues that may have company-wide impact
• Requires in-depth knowledge of the functional area, business strategies, and the company’s goals
• Must be self-motivated and detail-oriented
• Ability to quickly learn and think independently
• Excellent leadership, coaching and employee development skills
• Ability to effectively lead a team of statistical programmers with demonstrated proficiency in the hiring, training, and supervision of in-house and contract statistical programmers
• Excellent interpersonal & communication skills with the ability to interact professionally and effectively with peers, management, and leadership both within and outside the Company
• Ability to work with a team of individuals to meet organizational goals
• Possesses industry-leading knowledge pertaining to clinical and regulatory aspects of a pharmaceutical company.
• Evaluates key business / scientific challenges and completes complex, ambiguous initiatives having cross-functional impact
• Ability to apply advanced analytical thought and judgement
• Ability to work in a cross-functional team and a matrix environment
• Excellent organizational and time management skills with the ability to work independently and coordinate workload, under pressure, and in a team environment to meet established deadlines
• Excellent interpersonal skills and problem-solving capabilities
• Demonstrated leadership of enterprise-level evidence strategies, complex cross-functional programs, and people leaders.
• Deep understanding of regulatory, HTA, payer, and market access evidence requirements.
• Strong communication, influence, and stakeholder management skills.

Responsibilities

• Define and lead enterprise-wide epidemiology and RWE strategy, ensuring alignment with corporate objectives and cross-functional priorities across R&D, Medical, Market Access, and Analytics.
• Establish and oversee functional governance, including methodological standards, evidence quality expectations, prioritization frameworks, and ways of working across therapeutic areas.
• Translate enterprise RWE strategy into portfolio- and therapeutic-area-level evidence plans supporting development, launch, and lifecycle management.
• Serve as a senior advisor to executive and cross-functional leadership on population health, disease epidemiology, and real-world evidence.
• Drive evidence strategies that directly support regulatory submissions, HTAs, reimbursement decisions, and global value demonstration.
• Lead, coach, and develop Directors, Managers, and senior scientific staff; ensure effective talent development and succession planning.
• Oversee functional resourcing and budget management to ensure efficient, compliant, and high-quality execution.
• Partner closely with R&D leadership to integrate RWE into Phase 3 trial design and late-stage development, including external control arms, endpoint validation, and contextualization of clinical outcomes.
• Provide functional scientific accountability for epidemiology and RWE components of late-stage development programs.
• Ensure rigorous epidemiologic and observational methodologies are applied consistently across programs.
• Collaborate with Drug Safety and Pharmacovigilance (DSPV) on epidemiologic analyses supporting background rates, safety surveillance, post-marketing commitments, and risk assessment.
• Provide strategic oversight and input into clinical plans, publications, and integrated evidence strategies.
• Partner with HEOR and Market Access leadership to generate fit-for-purpose RWE demonstrating clinical value, effectiveness, cost-effectiveness, and budget impact.
• Ensure RWE outputs meet global payer, HTA, and regulatory evidentiary expectations, anticipating evolving requirements.
• Serve as a primary functional representative in scientific advice meetings and evidence discussions with regulatory agencies and HTA bodies.
• Engage and influence external stakeholders including regulators, academic experts, data partners, industry consortia, and advisory boards.
• Represent the Epidemiology & RWE function in governance forums, internal and external scientific engagements.
• Oversee and ensure consistency, scientific integrity, and quality of all epidemiology and observational research programs.
• Contribute to regulatory submission planning, including data strategies, integrated summaries, and evidence positioning.
• Develop and maintain functional processes, SOPs, and compliance frameworks to support scalable and high-quality evidence generation.
• Serve as the escalation point for complex scientific, regulatory, or payer-facing evidence issues.
• Perform other duties as assigned.

Benefits

• retirement savings plan (with company match)
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Director