Software Engineer II

Alnylam Pharmaceuticals•Cambridge, MA

22h•Hybrid

About The Position

The Research Informatics group is looking for a Software Engineer II to develop, maintain, and support web applications and tools utilized by Research, Early Development, and other groups within Alnylam. These tools directly support the discovery and development of RNAi therapeutics, enabling scientists to analyze data, make decisions, and accelerate progress toward new medicines. Because RNAi is a relatively new therapeutic modality, much of our work involves building custom software, ranging from data pipelines and APIs to user-facing applications and visualizations. We are also expanding our internal AI platform, including tools for natural language querying, structured data access (e.g., text-to-SQL), and working with unstructured data. Engineers on the team contribute to these systems and help integrate them into scientific workflows. This role is a good fit for someone early in their career who has some professional experience and is excited to take on increasing ownership, contribute to real-world scientific problems, and grow within a collaborative engineering team. This position is hybrid and will be primarily located in Cambridge, MA.

Requirements

BS in Computer Science or equivalent experience
1-3 years of professional software development experience
Strong fundamentals in programming, debugging, unit testing, and problem solving
Familiarity with version control (Git)
Understanding of web application architecture (client/server interactions, APIs)
Experience with one or more of the following: Python, JavaScript / TypeScript, SQL

Nice To Haves

Experience with Flask or similar backend frameworks
React or modern frontend frameworks
AWS or other cloud platforms
SQLAlchemy or ORM tooling
Docker or containerization
Exposure to AI-powered tools or data workflows
Familiarity with agile methodologies
Strong communication skills and ability to work with both technical and non-technical stakeholders
Eagerness to learn and grow in a collaborative environment

Responsibilities

Work with scientists and internal users to understand needs and help design and implement software solutions
Build, test, debug, and maintain web applications, APIs, and data-driven tools
Ability to work independently on well-defined tasks and collaborate on more complex projects
Contribute to the design and improvement of existing systems and workflows
Write clear documentation (design notes, technical specs, diagrams)
Participate in code reviews and follow established engineering best practices
Collaborate with the team through agile ceremonies (standups, sprint planning)