Shared Sr Research Services Technologist- Santos and Vakoc Labs

St. Jude Children's Research Hospital•Memphis, TN

2d•Onsite

About The Position

The laboratories of Drs. Camila dos Santos and Christopher Vakoc at St. Jude Children’s Research Hospital is seeking a highly motivated, organized, and technically skilled Shared Senior Research Services Technologist to provide advanced technical support in vivo research programs across both laboratories. This position will be shared between the two groups and will play an important role in establishing, maintaining, and executing murine studies in a collaborative and fast-paced research environment. We are looking for a candidate with strong hands-on experience in murine work, excellent attention to detail, and the ability to manage complex colony and experimental workflows with care and precision. The ideal candidate will be dependable, proactive, and comfortable working closely with trainees, staff, and principal investigators across two dynamic laboratories. This position offers the opportunity to contribute to complementary research programs in cancer biology, epigenetics, and disease modeling. The dos Santos Lab studies how genetic and non-genetic factors, including pregnancy, inflammation, and aging, influence breast cancer risk and progression, with a strong emphasis on cancer prevention and interception. The Vakoc Lab focuses on chromatin regulation and transcriptional control in cancer, using functional genomics and in vivo models to identify therapeutic vulnerabilities. Together, these laboratories offer a research environment spanning tumor initiation, lineage regulation, epigenetics, and translational disease modeling. The Senior Research Services Technologist will help build and support the in vivo infrastructure of both labs and will be expected to maintain high standards of technical rigor, organization, animal welfare, and regulatory compliance.

Requirements

High School Diploma/GED required.
Minimum requirement: 5+ years of experience in a professional murine care facility (e.g, zoo, veterinary clinic, laboratory murine facility) with High School Diploma/GED.
Experience Exception: 4+ years of experience with Associate's degree
Experience Exception: 2+ years of experience with Bachelor's degree.
ALAT certification required within 18 months

Nice To Haves

Associate's/Bachelor's degree in Lab Murine Science, Biology, Toxicology, or Agricultural preferred.
Prior experience within the ARC unit (e.g., murine handling and restraint; murine health monitoring; operation and sanitization/sterilization of equipment; sample collection) preferred.
Experience working with applicable regulations and policies regarding In Vivo research(e.g., ILAR Guide for the Care and Use of Laboratory Murine, USDA Welfare Act and Regulations) preferred.
Experience working with ARC or comparable software systems and databases for maintenance/review of documentation/records preferred.
Proven performance in earlier role/ comparable role
Laboratory Murine Technician (LAT) preferred.
Experience breeding and maintaining transgenic or knockout murine strains
Experience with genotyping workflows and colony tracking systems
Experience with tumor studies, transplantation experiments, drug dosing, or treatment studies in murine
Experience with tissue harvesting, necropsy, blood collection, or biospecimen collection
Experience with anesthesia, euthanasia, or specialized injection techniques
Familiarity with biosafety procedures, PPE requirements, and institutional murine compliance standards

Responsibilities

Manage murine colonies for two laboratories, including breeding, weaning, ear tagging, genotyping coordination, and accurate record keeping
Perform routine husbandry and handling activities in accordance with institutional standards and approved protocols.
Monitor murine health and communicate potential concerns promptly and appropriately
Develop and execute breeding strategies for transgenic, knockout, and other genetically engineered murine models
Perform experimental procedures in In vivo models, including injections, drug administration, dosing, euthanasia, tissue collection, and other in vivo techniques as needed
Support tumor studies, transplantation experiments, treatment studies, and related murine workflows
Perform necropsy, sample collection, and specimen processing for downstream analysis by laboratory members
Monitor tumor growth, study timelines, and experimental cohorts, while maintaining clear and accurate study documentation
Maintain cage cards, colony records, study logs, sample tracking, and other required documentation for assigned work
Assist with development, implementation, and maintenance of standard operating procedures and organizational systems for m-based work
Coordinate with institutional murine resources staff and maintain compliance with IACUC protocols and all relevant husbandry care and use regulations
Monitor and maintain inventories of murine-related reagents, supplies, PPE, and equipment needed for ongoing studies
Help establish efficient workflows as both laboratories grow
Assist with training and guiding newer lab members in standard mouse handling procedures and murine workflow practices where appropriate