SERM Senior Scientific Director, Oncology

GSK • Upper Providence, PA

1d • $217,800 - $363,000 • Hybrid

About The Position

Provides advanced scientific expertise in the safety evaluation and risk management of key GSK oncology assets in clinical development. Leads the identification, assessment, and communication of safety risks to ensure robust benefit-risk profiles and protection of patients globally. This role shapes safety strategy for innovative oncology therapies and supports high-quality, timely decisions and proactive risk mitigation across the portfolio through cross-functional partnership.

Requirements

• Degree in a health or life sciences discipline, such as a Bachelor of Science, PharmD, MD, PhD, or equivalent.
• At least 5 years of experience in pharmacovigilance, drug safety, or a related safety evaluation role in the pharmaceutical or biotech industry.
• Practical experience in signal detection, safety surveillance, and risk management across clinical development and post-marketing.
• Knowledge of global pharmacovigilance requirements and drug development processes.
• Strong clinical or scientific judgment, with experience interpreting clinical and safety data.

Nice To Haves

• Advanced degree (PharmD, PhD, MD) or equivalent clinical qualification.
• 10 or more years of pharmacovigilance or medical safety experience.
• Experience preparing regulatory safety documents and participating in regulatory interactions.
• Experience leading safety activities in a therapeutic area relevant to the role.
• Demonstrated ability to lead and influence cross-functional teams in a matrix setting.
• Experience supporting inspections, audits, and readiness activities.

Responsibilities

• Lead pharmacovigilance activities and risk mitigation strategies for assigned oncology assets and clinical trials.
• Drive the evaluation and interpretation of safety data, including signal detection and assessment.
• Develop strategic approaches for safety issue evaluation within clinical development programs.
• Contribute to safety components of global regulatory submissions, including INDs, DSURs, and IBs.
• Perform literature reviews, clinical data synthesis, and integrated safety analyses to inform decision-making.
• Ensure high-quality, timely delivery of outputs while managing multiple priorities.
• Represent Safety Evaluation & Risk Management (SERM) on Clinical Matrix and Project Teams.
• Lead cross-functional efforts to address urgent and complex product safety issues.
• Partner with Safety Physicians and stakeholders to prepare and present at Safety Review Team (SRT) meetings.
• Escalate emerging safety issues to senior leadership and governance bodies as appropriate.
• Build strong working relationships and lead effectively within a global matrix environment.
• Mentor and coach junior team members as applicable.
• Present safety recommendations and emerging risks to senior governance committees with clarity and impact.
• Represent GSK in interactions with regulatory authorities, external experts, and partners.
• Apply strategic thinking to evaluate internal and external factors influencing safety decisions.
• Contribute to long-term safety and clinical development strategies.
• Drive continuous improvement by introducing innovative approaches to safety evaluation and processes.
• Communicate complex scientific information effectively to diverse audiences.

Benefits

• Annual bonus.
• Eligibility to participate in a share-based long-term incentive program, dependent on role level.
• Health care and other insurance benefits for employees and their families.
• Retirement benefits.
• Paid holidays.
• Vacation.
• Paid caregiver, parental, and medical leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior