Senior Software Engineer

Heartflow•San Francisco, CA

About The Position

Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare. Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide. We are looking for a Senior Software Engineer to join our world-class engineering team. In this role, you will help design and develop cloud-based services and modern web applications that power the next generation of Heartflow technologies, including a new orchestration pipeline, which will drive critical workflows across the company. You will work cross-functionally with Software Engineers, Product Managers, Quality Assurance, Usability Designers, Process Engineers, and Regulatory to create impactful internal applications and infrastructure. This role offers the opportunity to contribute meaningfully to the design, scalability, and performance of our platforms, while ensuring regulatory compliance in a fast-paced, innovative environment.

Requirements

BS in Computer Science or a related technical field + 5 years of experience; OR MS/PhD in Computer Science or related field + 3 years; OR equivalent practical experience as a full-stack software engineer.
Proficiency in TypeScript or JavaScript.
Strong development experience with Python.
Strong cloud development experience (preferably AWS).
Familiarity with modern web frameworks (Django & js strongly preferred, but Angular/React is acceptable).
Deep understanding of backend and frontend security best practices.
Strong problem-solving skills with the ability to analyze and resolve complex issues.
Solid grasp of modern software development methodologies including CI/CD, testing, and Agile practices.
Excellent communication and collaboration skills.

Nice To Haves

Advanced proficiency in: Python, Django, JavaScript, TypeScript, js
Nginx, Pytest, GitHub, GitHub Actions
Hands-on experience designing and building orchestration pipelines.
Strong AWS experience with services such as: Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora (MySQL 8.0+)
Demonstrated success in delivering cloud-native APIs, scalable web apps, and complex distributed systems.
Experience developing regulated medical software (e.g., Software as a Medical Device) in compliance with FDA

Responsibilities

Lead end-to-end feature development across the full technology stack
Independent, end-to-end ownership of the design, development, testing, and maintenance of robust APIs (Python, AWS), interactive web applications (Django backend and Vue.js frontend), pipeline orchestrations, and associated infrastructure.
Contribute to the long-term technical roadmap by providing architectural feedback that ensures current systems remain compatible with future orchestration goals.
Mentor junior engineers and contribute to the technical excellence of our team.
Make data-driven decisions while practicing creative problem solving.
Write clean, maintainable, well-documented code with a focus on high-stakes quality, performance, and user experience.
Improve infrastructure components including orchestration pipelines, test frameworks, and CI/CD workflows.
Lead the technical integration of emerging tools, such as Agentic AI frameworks, to automate internal developer workflows and improve team velocity.
Contribute to releases of application deployments and participate in on-call production support as needed.
Collaborate cross-functionally with Product, Design, and Engineering stakeholders to define and implement product features.
Participate in code reviews and champion engineering best practices.
Contribute to a culture of technical excellence, innovation, best practices, and continuous improvement.
Ensure compliance with FDA regulations for medical software and supporting systems, including documentation and quality assurance processes.